Publications by authors named "Sedat Demiriz"
Article Synopsis
- - The population of Newfoundland and Labrador primarily descends from 18th-19th century settlers from England and Ireland, with genetic studies showing it's an isolated founder population with limited diversity.
- - A study analyzed 1,110 Y chromosomes and identified 160 distinct haplogroups, predominantly of the R1b type, mirroring the haplogroups found in English and Irish populations.
- - The research highlighted geographical and religious clustering within the population, indicating that historical settlement patterns and limited immigration have shaped the genetic structure of Newfoundland and Labrador.
The founder population of Newfoundland and Labrador (NL) is a unique genetic resource, in part due to its geographic and cultural isolation, where historical records describe a migration of European settlers, primarily from Ireland and England, to NL in the 18th and 19th centuries. Whilst its historical isolation, and increased prevalence of certain monogenic disorders are well appreciated, details of the fine-scale genetic structure and ancestry of the population are lacking. Understanding the genetic origins and background of functional, disease causing, genetic variants would aid genetic mapping efforts in the Province.
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