Publications by authors named "Seda Gokgoz"
Article Synopsis
- - The study investigated the protective effects of ozone on liver damage caused by sepsis in rats, using a model induced by cecal ligation and perforation (CLP).
- - Rats were divided into groups to compare the effects of ozone treatment before and after CLP, showing that pre-treatment significantly reduced liver injury markers and inflammatory responses.
- - Results indicated that ozone therapy led to lower levels of key liver injury markers and inflammatory cytokines while boosting antioxidant activity, suggesting its potential role in protecting the liver during sepsis.
Objective: Pancreatic surgeries inherently cause ischemia-reperfusion (IR) injury, affecting not only the pancreas but also distant organs. This study was conducted to explore the potential use of dexmedetomidine, a sedative with antiapoptotic, anti-inflammatory, and antioxidant properties, in mitigating the impacts of pancreatic IR on kidney and liver tissues.
Methods: A total of 24 rats were randomly divided into four groups: control (C), dexmedetomidine (D), ischemia reperfusion (IR), and dexmedetomidine ischemia reperfusion (D-IR).