Publications by authors named "Seco A"

This study aimed to assess the environmental and economic performance of an ultrafiltration (UF) tertiary treatment of effluent from an urban wastewater treatment facility. Data from a UF demonstration plant composed of commercially available equipment, including industrial hollow-fiber membranes was used to project a full-scale facility. The results from the demonstration plant recommended different ranges of transmembrane fluxes and sparging air demands under summer and winter conditions to prevent excessive fouling.

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Article Synopsis
  • Eclampsia, a rare and serious complication of hypertensive disorders in pregnancy, shows an incidence of 2.8 per 10,000 births, highlighting its potential for being preventable with better care.
  • A study analyzed the care quality provided to women with eclampsia compared to those with severe maternal morbidity from non-eclamptic high blood pressure and found significant inadequacies in antenatal (39% inadequate), pre-eclampsia (76% inadequate), and eclampsia care (50% inadequate).
  • The findings indicate a critical need for improved, evidence-based standards for managing hypertensive disorders during pregnancy to prevent adverse outcomes for mothers and their babies.
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The kinetics, thermodynamics, and degradation of malvidin mono- and diglucosides were studied following a holistic approach by extending to the basic medium. In acidic conditions, the reversible kinetics of the flavylium cation toward the equilibrium is controlled by the hydration and - isomerization steps, while in the basic medium, the OH nucleophilic addition to the anionic quinoidal bases is the slowest step. There is a pH range (transition pHs), between the acidic and basic paradigms, that includes physiological pH (7.

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  • - The study focused on identifying risk factors for placenta accreta spectrum (PAS) in women with previous cesarean deliveries and either placenta previa or a low-lying placenta, using data from 2013 to 2015.
  • - Out of over 520,000 deliveries, 396 women met the criteria, with 108 diagnosed with PAS, showing a significant correlation between the number of prior cesareans and the rate of PAS, which could range from 5% to 63%.
  • - Key risk factors for developing PAS included having a BMI of 30 or higher, previous uterine surgeries, past postpartum hemorrhage, multiple cesarean deliveries, and presence of placenta previa, indicating that risk stratification is
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Recycling carbon-rich wastes into high-value platform chemicals through biological processes provides a sustainable alternative to petrochemicals. Cupriavidus necator, known for converting carbon dioxide (CO) into polyhydroxyalkanoates (PHA) was studied for the first time using biogas streams as the sole carbon source. The bacterium efficiently consumed biogenic CO from raw biogas with methane at high concentrations (50%) proving non-toxic.

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Objectives: Among women with severe PPH (sPPH) in France and the Netherlands, we compared incidence of adverse maternal outcome (major obstetric hemorrhage (≥2.5L blood loss) and/or hysterectomy and/or mortality) by mode of delivery. Second, we compared use and timing of resuscitation and transfusion management, second-line uterotonics and uterine-sparing interventions (intra-uterine tamponade, compression sutures, vascular ligation, arterial embolization) by mode of delivery.

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Objective: To explore the association between induction of labor (IOL) and postpartum hemorrhage (PPH) after vaginal delivery.

Methods: We included women from the merged database of three randomized prospective trials (TRACOR, CYTOCINON, and TRAAP) that measured postpartum blood loss precisely, with standardized methods. IOL was considered overall and according to its method.

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Background: Incontinence occurs frequently in the postpartum period. Several theoretical pathophysiological models may underlie the hypothesis that different types of management of the active phase of the second stage of labor have different effects on pelvic floor muscles and thus perhaps affect urinary and anal continence.

Objective: This study aimed to evaluate the impact of "moderate pushing" on the occurrence of urinary or anal incontinence compared with "intensive pushing," and to determine the factors associated with incontinence at 6 months postpartum.

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Human urine has a high chemical oxygen demand (COD) content which makes anaerobic treatments potentially appropriate for the management of yellow waters, allowing for energy recovery. However, its high N content makes this treatment challenging. The present work studied the viability of performing an anaerobic digestion process for COD valorization on a real (not synthetic) urine stream at laboratory scale.

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Aim: To evaluate the effect of faster aspart over glycaemic variability in type 1 diabetes (T1D) patients treated with sensor-augmented pump (SAP) in a real-world scenario.

Methods: Observational study with SAP-treated adult T1D patients treated with faster aspart for three months. The primary endpoint was the mean amplitude of glucose excursions (MAGE).

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Objective: To evaluate the risk of disseminated intravascular coagulation (DIC) in postpartum hemorrhage (PPH) associated with intrauterine infection.

Material And Methods: A retrospective cohort study of pregnancies complicated by PPH performed at a tertiary academic center in France from 2017 through 2021. Patients giving birth after 22 weeks of gestation with PPH were eligible.

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Objective: To assess the incidence and risk factors for severe postpartum haemorrhage (PPH) in women with an anterior low-lying or praevia placenta, prior caesarean and no prenatal suspicion of placenta accreta spectrum (PAS).

Design: Population-based study in 176 maternity units in France.

Population: All women with anterior low-lying (0-19 mm from the cervical internal os) or praevia placenta, diagnosed prospectively before birth, prior caesarean and no prenatal suspicion of PAS.

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Article Synopsis
  • The study investigates the effects of intrauterine balloon tamponade when used along with second-line uterotonics versus after the failure of second-line treatment in managing severe postpartum hemorrhage for women who had vaginal deliveries.
  • Conducted across 18 hospitals with 403 participants, it focuses on women with postpartum hemorrhage that did not respond to first-line treatment (oxytocin) and required additional intervention.
  • The primary outcome measured was the need for blood transfusions or excessive blood loss, with secondary outcomes including the frequency of significant blood loss, transfusions, invasive procedures, and ICU transfers.
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A mechanistic model describing the key interactions occurring in microalgae-bacteria consortia systems was developed and validated. The proposed model includes the most relevant features of microalgae, such as light dependence, endogenous respiration, growth, and nutrient consumption for different nutrient sources. The model is coupled to the plant-wide model BNRM2, including heterotrophic and nitrifying bacteria, and chemical precipitation processes, among others.

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Three inhibitors targeting different microorganisms, both from Archaea and Bacteria domains, were evaluated for their effect on CO biomethanation: sodium ionophore III (ETH2120), carbon monoxide (CO), and sodium 2-bromoethanesulfonate (BES). This study examines how these compounds affect the anaerobic digestion microbiome in a biogas upgrading process. While archaea were observed in all experiments, methane was produced only when adding ETH2120 or CO, not when adding BES, suggesting archaea were in an inactivated state.

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This study aimed to evaluate the feasibility of applying a commercial porous membrane to direct filtration of municipal wastewater. The effects of membrane pore size (MF and UF), treated influent (raw wastewater and the primary settler effluent of a municipal wastewater treatment plant) and operating solids concentration (about 1 and 2.6 g L) were evaluated on a demonstration plant.

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Objective: To assess the association between gestational age at delivery and postpartum severe acute maternal morbidity (SAMM) in twin pregnancies.

Methods: Secondary analysis of the JUMODA cohort, a national, prospective, population-based study of twin pregnancies in France. We excluded women with delivery before 32 weeks of pregnancy, with a fetal death or medical termination, with antepartum SAMM, or with antepartum conditions responsible for postpartum SAMM.

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Objective: To characterize the strength and patterns of association between birth weights and severe postpartum hemorrhage in twin pregnancies.

Methods: This was a secondary analysis of the JUMODA (JUmeaux Mode d'Accouchement) cohort, a national, prospective, population-based study of twin deliveries, conducted from February 2014 to March 2015 in France. We excluded patients with a fetal death, medically indicated termination of pregnancy, antepartum hemorrhage, placenta previa, placental abruption, or missing birth weight.

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To develop a new tool to assess the global quality of care for post-partum hemorrhage (PPH)-the leading preventable cause of maternal mortality worldwide-and to identify characteristics of maternity units associated with inadequate PPH management. This is a secondary analysis of the EPIMOMS population-based study conducted in 2012-2013 in 119 french maternity units (182,309 women who gave birth). We included women with severe PPH.

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The aim of this study was to assess the feasibility of using dynamic membranes for direct filtration of municipal wastewater. The influence of different alternative supporting materials (one or two layers of flat open monofilament woven polyamide meshes with 1 or 5 µm of pore size) was studied. A stable short-term self-forming DM was achieved (from some hours to 3 days) regardless of the supporting material used, producing relatively similar permeate qualities (total suspended solids, chemical oxygen demand, total nitrogen, total phosphorous and turbidity of 67-88 mg L, 155-186 mg L, 48.

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Stopped flow corroborated by UV-vis measurements allowed for the calculation of the copigmentation constants of delphinidin 3--glucoside with the neutral (CP) and negatively charged CP(-) forms of chlorogenic acid. Solutions of delphinidin 3--glucoside in the absence and presence of the copigment were equilibrated at several pH values in the acidic region, pH < 6, and reverse pH jumps monitored by stopped flow were carried out by adding sufficient acid to give flavylium cation at pH ≤ 1. This procedure allows for the separation of three contributions: (i) all flavylium cation and quinoidal base species, (ii) all hemiketal species, and (iii) all -chalcone species.

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Intermolecular copigmentation of malvidin-3--glucoside with caffeine was studied using a holistic procedure that includes the extension to basic pH values. In moderately basic solutions (7.5 < pH < 9.

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Article Synopsis
  • The study examined the effects of "moderate" vs "intensive" pushing during the second stage of labor on neonatal health outcomes.
  • The research involved 1710 first-time mothers and compared outcomes between two groups: one with moderated pushing and another with intensive pushing, assessing factors like neonatal morbidity and mode of delivery.
  • Results showed that while the neonatal morbidity was slightly lower in the moderate group (18.9%) compared to the intensive group (20.6%), those in the moderate group pushed longer, averaging 38.8 minutes compared to 28.6 minutes for the intensive group.
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Study Objective: Fibrinogen concentrate is used to treat severe postpartum hemorrhage despite limited evidence of its effectiveness in obstetric settings. We aimed to explore the association between its administration and maternal outcomes in women with severe postpartum hemorrhage.

Design, Setting And Patients: This secondary analysis of the EPIMOMS prospective population-based study, exploring severe maternal morbidity, as defined by national expert consensus (2012-2013, 182,309 deliveries, France), included all women with severe postpartum hemorrhage and transfused with red blood cells during active bleeding.

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