Publications by authors named "Sebastien Speeckaert"
J Biomol Screen
July 2011
Article Synopsis
- - The study evaluates the use of impedance-based label-free technology for drug discovery, highlighting its noninvasive nature and ability to measure key cellular processes like proliferation and cytotoxicity.
- - Results from 31 experiments show that the RTCA platform produces reproducible data for various cell types, with a specific focus on HepG2 and its response to different compounds, achieving high correlation values.
- - While the technology shows promise and efficiency, the research acknowledges limitations, such as potential confounding factors affecting analysis and a narrow range of compounds tested for correlation with traditional toxicity endpoints.
