Publications by authors named "Sebastien Filippas-Ntekouan"

Article Synopsis
  • Serum osmolal gap measurement is helpful in diagnosing toxic alcohol ingestion, with normal levels usually below 10 mOsm/kg and values above 20 mOsm/kg indicating possible toxicity from various substances, including methanol and ethylene glycol.
  • A case is presented involving an 18-year-old male who, after binge drinking, experienced severe ethanol intoxication characterized by a comatose state, high anion gap metabolic acidosis, and an extremely elevated osmolal gap of 91 mOsm/kg.
  • The findings suggest that acute, isolated ethanol intoxication can cause significant changes in osmolal gap levels, and clinicians should consider this in patients with high anion gap metabolic acidosis alongside elevated osmolal
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Cirrhotic patients are known to be particularly susceptible to infectious complications that may vary according to regional endemic patterns. Brucellosis, a common zoonosis with worldwide distribution, exhibits a predilection for the reticuloendothelial system and thus resulting in hepatic involvement. We describe three cirrhotic patients in whom acute brucellosis and/or its treatment served as the triggering factor of hepatic decompensation, with deleterious effects.

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Article Synopsis
  • * Blocking SGLT1 can lower blood sugar levels and potentially protect the heart by reducing harmful substances, but it also comes with risks like diarrhea and complications in managing low blood sugar.
  • * Overall, inhibiting SGLT1 presents both benefits and drawbacks, making it a complex strategy in diabetes management that needs careful consideration.
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