Correlation between molecular signals and bone bonding to titanium implants.

Objectives: A better understanding of the biological processes controlling osseointegration at the bone-to-implant interface is needed. The aim of this study was to examine which are the molecular and biochemical variables that are significantly related to osseointegration, using multiple regression analysis.

Materials And Methods: Titanium coins were placed into the tibial cortical bone of New Zealand White rabbits and evaluated using pull-out test after 4 and 8 weeks of healing.

Identification of early response genes to roughness and fluoride modification of titanium implants in human osteoblasts.

Purpose: Tissue response after implantation determines the success of the healing process. This response is not only dependent on the chemical properties of the implant surface but also by the surface topography or its roughness. Although in vitro and in vivo studies show improved results with rough- and fluoride-modified implants, the mechanisms behind these findings are still unknown.

Wear model simulating clinical abrasion on composite filling materials.

The aim of this study was to establish a wear model for testing composite filling materials with abrasion properties closer to a clinical situation. In addition, the model was used to evaluate the effect of filler volume and particle size on surface roughness and wear resistance. Each incisor tooth was prepared with nine identical standardized cavities with respect to depth, diameter, and angle.

Controlled electro-implementation of fluoride in titanium implant surfaces enhances cortical bone formation and mineralization.

Previous studies have shown that bone-to-implant attachment of titanium implants to cortical bone is improved when the surface is modified with hydrofluoric acid. The aim of this study was to investigate if biological factors are involved in the improved retention of these implants. Fluoride was implemented in implant surfaces by cathodic reduction with increasing concentrations of HF in the electrolyte.