Chemotherapeutic decontamination of dental implants colonized by mature multispecies oral biofilm.

Aim: No studies have tested disinfectants on mature multispecies oral biofilms on titanium substrata. The aim of this study was to investigate the efficacy of commonly used antimicrobial agents in decontamination of multispecies mature oral biofilm on sandblasted, large-grit, acid-etched (SLA) titanium implants.

Methods: SLA titanium disks were inoculated with dental plaque and cultured anaerobically for 21 days.