Publications by authors named "Sebastien Champagne"

Article Synopsis
  • - This review compares the effectiveness and safety of sleep medications (hypnotics) in older adults (65+) versus younger adults (<65) for improving sleep quality and overall safety.
  • - Out of 70 clinical trials analyzed with nearly 18,000 participants, older adults had a smaller improvement in sleep quality and lower tolerance for medications compared to younger adults.
  • - The study suggests that some hypnotics may be less effective for seniors and emphasizes the need for future research to consider factors like multiple health issues and multiple medications in older populations.
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Absorbable metals have the potential to serve as the next generation of temporary medical implant devices by safely dissolving in the human body upon vascular tissue healing and bone regeneration. Their implementation in the market could greatly reduce the need of costly and risky additional surgeries for either implant replacement or removal, often required in current permanent implants. Despite the extensive research done over the last two decades on magnesium (Mg) and iron (Fe) based alloys, they have not generally shown a satisfactory combination of mechanical properties, biocompatibility and controlled degradation rate in the physiological environment.

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Absorbable metals have potential for making in-demand rigid temporary stents for the treatment of urinary tract obstruction, where polymers have reached their limits. In this work, in vitro degradation behavior of absorbable zinc alloys in artificial urine was studied using electrochemical methods and advanced surface characterization techniques with a comparison to a magnesium alloy. The results showed that pure zinc and its alloys (Zn⁻0.

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