Morphoanatomical, Histochemical, and Essential Oil Composition of the Codd. (Lamiaceae).

is a medicinal and aromatic plant used in traditional and alternative medicine. In this study, leaves of were collected in two cities of the state of Pará, "Quatipuru" and "Barcarena", and were used with the objective of analyzing, through morphoanatomical data and histochemical and phytochemical studies of essential oil, the samples present structural differences and differences in their chemical composition. Anatomical and histochemical analyses were performed by transverse, using longitudinal sections of 8 μm to 10 μm to perform epidermal dissociation, diaphonization, and tests to identify classes of secondary metabolites.

In Silico Evaluation of the Antimicrobial Activity of Thymol-Major Compounds in the Essential Oil of Mart. & Schauer (Verbenaceae).

In this paper, we evaluated the drug-receptor interactions responsible for the antimicrobial activity of thymol, the major compound present in the essential oil (EO) of Mart. & Schauer (Verbenaceae). It was previously reported that this EO exhibits antimicrobial activity against (), (), and ().

Chemical Composition and Antioxidant Activity of Essential Oils from Leaves of Two Specimens of DC.

DC. belongs to the family, which is present in almost all of Brazil. This species is popularly known as or and is used in folk medicine to treat gastrointestinal problems.

Drying Effects on Chemical Composition and Antioxidant Activity of Essential Oil, a Natural Source of Thymol.

Leaves of (Verbenaceae) were dried in an oven at 40, 50 and 60 °C and the kinetic of drying and the influence of the drying process on the chemical composition, yield, and DPPH radical scavenging activity of the obtained essential oils were evaluated. The composition of the essential oils was determined with gas chromatography-mass spectrometry and gas chromatography-flame ionization detection analyses. The influence of drying on the chemical composition of the essential oils of was evaluated by multivariate analysis, and their antioxidant activity was investigated via the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay.

First report on the DC. Essential oil and identification of potential biological targets of its major compounds.

In the present study, the essential oil (EO) of DC. or was extracted by hydrodistillation, and the identification and quantification of volatile compounds were performed by GC-MS and GC-FID. leaves were collected from the Magalhães Barata, northeast of the State of Pará (Brazil) in March and September of 2019.

Extraction Yield, Chemical Composition, Preliminary Toxicity of Bignonia nocturna (Bignoniaceae) Essential Oil and in Silico Evaluation of the Interaction.

Bignonia nocturna (Bignoniaceae) is a plant used for medicinal purposes by the Amazonian indigenous peoples. To date, there have been no reported studies on its toxicity. The present study aimed to evaluate the chemical composition of essential oils obtained from Bignonia nocturna by different extraction techniques.

Chemical Composition, Antimicrobial Properties of Essential Oil and a Molecular Docking and Dynamics Molecular Study of its Major Chemical Constituent.

The essential oil of was obtained by hydrodistillation. The identification of the chemical compounds was performed by gas chromatography coupled with mass spectrometry (GC/MS). Antimicrobial activity was investigated for four microorganisms: (ATCC 3440), (ATCC 4083), (ATCC 25922), and (ATCC-10231).

Physiological performance and chemical compositions of the L. (Apiaceae) essential oil cultivated with different fertilizer sources.

The present work proposed an evaluation of the physiological performance, yield and chemical profile of the essential oil obtained from leaves and roots of L. (Apiaceae) cultivated using different fertilizer sources. The other gas exchange and chlorophyll a fluorescence parameter was not different, suggested that the photosystem II was not affected by the different fertilizer sources.

First Report on Yield and Chemical Composition of Essential Oil Extracted from DC (Myrtaceae) from the Brazilian Amazon.

The essential oil (EO) of plants of the Myrtaceae family has diverse chemical composition and several applications. However, data on the oil yield, its composition, and its complete chemistry are still unavailable for some species belonging to this family, such as DC. In this study, the chemical compositions of the EOs of were evaluated by using gas chromatography (GC) alone and gas chromatography coupled with mass spectrometry (GC-MS).

Insight into the Interaction Mechanism of Nicotine, NNK, and NNN with Cytochrome P450 2A13 Based on Molecular Dynamics Simulation.

Tobacco smoke contains various cancer-causing toxic substances, including nicotine and nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and '-nitrosonornicotine (NNN). The cytochrome 2A13 is involved in nicotine metabolism and in the activation of the pro-carcinogenic agents NNK and NNN, by means of α-hydroxylation reactions. Despite the significance of cytochrome 2A13 in the biotransformation of these molecules, its conformational mechanism and the molecular basis involved in the process are not fully understood.

Chemical profile of Lippia thymoides, evaluation of the acetylcholinesterase inhibitory activity of its essential oil, and molecular docking and molecular dynamics simulations.

The essential oils of the fresh and dry flowers, leaves, branches, and roots of Lippia thymoides were obtained by hydrodistillation and analyzed using gas chromatography (GC) and GC-mass spectrometry (MS). The acetylcholinesterase inhibitory activity of the essential oil of fresh leaves was investigated on silica gel plates. The interactions of the key compounds with acetylcholinesterase were simulated by molecular docking and molecular dynamics studies.