Morphoanatomical, Histochemical, and Essential Oil Composition of the Codd. (Lamiaceae).

is a medicinal and aromatic plant used in traditional and alternative medicine. In this study, leaves of were collected in two cities of the state of Pará, "Quatipuru" and "Barcarena", and were used with the objective of analyzing, through morphoanatomical data and histochemical and phytochemical studies of essential oil, the samples present structural differences and differences in their chemical composition. Anatomical and histochemical analyses were performed by transverse, using longitudinal sections of 8 μm to 10 μm to perform epidermal dissociation, diaphonization, and tests to identify classes of secondary metabolites.

In Silico Evaluation of the Antimicrobial Activity of Thymol-Major Compounds in the Essential Oil of Mart. & Schauer (Verbenaceae).

In this paper, we evaluated the drug-receptor interactions responsible for the antimicrobial activity of thymol, the major compound present in the essential oil (EO) of Mart. & Schauer (Verbenaceae). It was previously reported that this EO exhibits antimicrobial activity against (), (), and ().

Chemical Composition and Antioxidant Activity of Essential Oils from Leaves of Two Specimens of DC.

DC. belongs to the family, which is present in almost all of Brazil. This species is popularly known as or and is used in folk medicine to treat gastrointestinal problems.

First report on the DC. Essential oil and identification of potential biological targets of its major compounds.

In the present study, the essential oil (EO) of DC. or was extracted by hydrodistillation, and the identification and quantification of volatile compounds were performed by GC-MS and GC-FID. leaves were collected from the Magalhães Barata, northeast of the State of Pará (Brazil) in March and September of 2019.

Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches.

Non-steroidal anti-inflammatory drugs are inhibitors of cyclooxygenase-2 (COX-2) that were developed in order to avoid the side effects of non-selective inhibitors of COX-1. Thus, the present study aims to identify new selective chemical entities for the COX-2 enzyme via molecular modeling approaches. The best pharmacophore model was used to identify compounds within the ZINC database.

Chemical Composition, Antimicrobial Properties of Essential Oil and a Molecular Docking and Dynamics Molecular Study of its Major Chemical Constituent.

The essential oil of was obtained by hydrodistillation. The identification of the chemical compounds was performed by gas chromatography coupled with mass spectrometry (GC/MS). Antimicrobial activity was investigated for four microorganisms: (ATCC 3440), (ATCC 4083), (ATCC 25922), and (ATCC-10231).

Physiological performance and chemical compositions of the L. (Apiaceae) essential oil cultivated with different fertilizer sources.

The present work proposed an evaluation of the physiological performance, yield and chemical profile of the essential oil obtained from leaves and roots of L. (Apiaceae) cultivated using different fertilizer sources. The other gas exchange and chlorophyll a fluorescence parameter was not different, suggested that the photosystem II was not affected by the different fertilizer sources.

First Report on Yield and Chemical Composition of Essential Oil Extracted from DC (Myrtaceae) from the Brazilian Amazon.

The essential oil (EO) of plants of the Myrtaceae family has diverse chemical composition and several applications. However, data on the oil yield, its composition, and its complete chemistry are still unavailable for some species belonging to this family, such as DC. In this study, the chemical compositions of the EOs of were evaluated by using gas chromatography (GC) alone and gas chromatography coupled with mass spectrometry (GC-MS).

Chemical profile of Lippia thymoides, evaluation of the acetylcholinesterase inhibitory activity of its essential oil, and molecular docking and molecular dynamics simulations.

The essential oils of the fresh and dry flowers, leaves, branches, and roots of Lippia thymoides were obtained by hydrodistillation and analyzed using gas chromatography (GC) and GC-mass spectrometry (MS). The acetylcholinesterase inhibitory activity of the essential oil of fresh leaves was investigated on silica gel plates. The interactions of the key compounds with acetylcholinesterase were simulated by molecular docking and molecular dynamics studies.

Planting and seasonal and circadian evaluation of a thymol-type oil from Lippia thymoides Mart. & Schauer.

Background: The oil and extracts of Lippia thymoides have been used for various medicinal and food applications. Entrepreneurs in the Amazon have been considering the economic exploitation of this plant. The present study evaluated the influence of the seasonal and circadian rhythm on the yield and composition of the essential oil of leaves and thin branches of a Lippia thymoides specimen cultivated in Abaetetuba, State of Pará, Brazil.