Microbiome differences in periodontal, peri-implant, and healthy sites: a cross-sectional pilot study.

Objectives: To explore microbial communities associated with health and disease status around teeth and dental implants.

Materials And Methods: A total of 10 healthy, 24 periodontitis, and 24 peri-implant sites from 24 patients were sequenced by next-generation sequencing. Microbial DNA was extracted and 16S rRNA gene was amplified.

Influence of kinematics and incidence angles on the cutting efficiency of two single-file nickel-titanium rotary instruments.

To compare the cutting efficiency of F6 Sky Taper (F6ST) and One Curve (OC) with different kinematics and cutting inclinations. Cutting efficiency of 80 new F6ST and OC was tested at 90° and 70° inclination in relation to the sample, in continuous rotation and reciprocation, against standardised gypsum samples for 120 seconds using a customised device. Data expressed as weight loss and length of the sample cut were analysed using two-way analysis of variance and Tukey t-test (P<.

Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection.

Different viral agents, such as herpesviruses, human papillomavirus, and Coxsackie virus, are responsible for primary oral lesions, while other viruses, such as human immunodeficiency virus, affect the oral cavity due to immune system weakness. Interestingly, it has been reported that coronavirus disease 2019 (COVID-19) patients can show cutaneous manifestations, including the oral cavity. However, the association between oral injuries and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is still unclear.

Influence of surrounding temperature and angle of file access on cyclic fatigue resistance of two single file nickel-titanium instruments.

The purpose of this study was to evaluate the influence of surrounding temperature and angle of file access on cyclic fatigue resistance of F6 SkyTaper (F6ST) and One Curve (OC). 120 new files #25.06 were tested at two insertion angles (0° and 20°) at room (20°C ± 1°C) and body (35°C ± 1°C) temperatures in a 16-mm stainless steel artificial canal (60° curvature and 5-mm radius), using a customised device.

Association among serum and salivary A. actinomycetemcomitans specific immunoglobulin antibodies and periodontitis.

Background: The aim of this study was to assess the association between serum and salivary Immunoglobulin (Ig) Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) specific antibodies in healthy controls (HC) and periodontitis (PT) patients. Furthermore, the objectives were to determine whether PT influenced serum A.

Analysis of Endothelin-1 Concentrations in Individuals with Periodontitis.

Endothelin 1 (ET-1) has been shown to have a key role in homeostasis and function of endothelium and maybe fundamental in the relationship between coronary heart disease (CHD) and periodontitis. In this trial, we assessed the influence on serum and salivary ET-1 levels of gingival health, CHD, periodontitis, or a combination of periodontitis-CHD. Clinical and periodontal parameters, were collected from periodontitis patients (n = 34), CHD patients (n = 34), periodontitis + CHD patients (n = 34), and from healthy patients (n = 34) together with saliva and serum samples.

Periodontitis and Tooth Loss Have Negative Systemic Impact on Circulating Progenitor Cell Levels: A Clinical Study.

The aim of the present study was to investigate the association and impact of periodontitis and tooth loss on a subtype of endothelial progenitor cell (EPC) levels (CD133/KDR). Furthermore, the objective was to determine if the periodontal status influenced CD133/KDR levels. In all, 88 patients with periodontitis and 79 healthy controls (HCs) were enrolled in the study.

Expression of Salivary and Serum Malondialdehyde and Lipid Profile of Patients with Periodontitis and Coronary Heart Disease.

Malondialdehyde (MAA) within a lipid pathway has been demonstrated to possess an important role in endothelial function that undergoes periodontitis and coronary heart disease (CHD) development. This study evaluated the impact of periodontitis, CHD, or a combination of both diseases (periodontitis + CHD) on salivary and serum MAA levels. The periodontal and clinical characteristics, serum, and saliva samples were collected from 32 healthy subjects, 34 patients with periodontitis, 33 patients with CHD, and 34 patients with periodontitis and CHD.

Analysis of the Effectiveness of Lornoxicam and Flurbiprofen on Management of Pain and Sequelae Following Third Molar Surgery: A Randomized, Controlled, Clinical Trial.

The aim of this study was to analyze the effectiveness of Lornoxicam and Flurbiprofen in reducing perioperative sequelae after impacted mandibular third molar surgery. Ninety-one patients who needed surgical extraction of an impacted mandibular third molar were selected for the study. All subjects were randomly allocated to receive one of the following treatments twice a day for 5 days after surgery: placebo ( = 29), Flurbiprofen ( = 31), or Lornoxicam ( = 31).

Treatment of bisphosphonate-related osteonecrosis of the jaws: presentation of a protocol and an observational longitudinal study of an Italian series of cases.

The aim of this study was to evaluate the efficacy of a treatment protocol for bisphosphonate-related osteonecrosis of the jaws (BRONJs). We conducted a longitudinal observational non-controlled study in 94 patients with confirmed BRONJ. Treatment was in two phases: supportive (antimicrobial mouth rinses, antibiotics, and anti-inflammatory steroids) to minimise infection and pain before the formation of a bony sequestrum; and surgical plus pharmacological treatment (sequestrectomy with antibiotic prophylaxis) after the sequestrum had developed.