Publications by authors named "Sebastian Winther"
Article Synopsis
- Revision total hip arthroplasty (rTHA) is complex, particularly with significant bone loss affecting implant stability, and this study focused on evaluating outcomes using an uncemented modular implant design in 100 patients.
- Out of the 101 hips analyzed, 51 had lower-grade bone defects (Paprosky types I-II) and 50 were more severe (types III-IV), with a follow-up averaging 5.8 years, assessing implant survival and clinical outcomes using various scoring measures.
- The findings revealed a high 5-year implant survival rate of 95%, with successful osseointegration in all hips and no significant subsidence; however, some complications occurred, including dislocations and fractures, but overall
Aims: Pelvic discontinuity is a rare but increasingly common complication of total hip arthroplasty (THA). This single-centre study evaluated the performance of custom-made triflange acetabular components in acetabular reconstruction with pelvic discontinuity by determining: 1) revision and overall implant survival rates; 2) discontinuity healing rate; and 3) Harris Hip Score (HHS).
Methods: Retrospectively collected data of 38 patients (39 hips) with pelvic discontinuity treated with revision THA using a custom-made triflange acetabular component were analyzed.
Ionotropic glutamate receptors (iGluRs) are involved in most of the fast excitatory synaptic transmission in the central nervous system. These receptors are important for learning and memory formation, but are also involved in the development of diseases such as Alzheimer's disease, epilepsy and depression. To understand the function of different types of iGluRs, selective agonists are invaluable as pharmacological tool compounds.
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