First report of a Chinese strain of coxsackie B3 virus infection in a newborn in Germany in 2011: a case report.

Introduction: Enteroviruses commonly encounter babies and children and infections present in a wide variety of symptoms ranging from asymptomatic infection, benign illness, and aseptic meningitis, hand-foot-and-mouth disease to severe life-threatening disease. Some newborns develop severe disease in the first 2 weeks of life and long-term sequelae may occur among survivors.

Case Presentation: We present a case report of a Caucasian newborn baby boy with severe encephalitis and systemic coxsackievirus B3 infection.

High DMBT1 concentrations in breast milk correlate with increased risk of infection in preterm and term neonates.

Background: Human milk contains immune molecules involved in the protection of newborns against infections. We analyzed the concentration of Deleted in Malignant Brain Tumors 1 (DMBT1), a protein with functions in innate immunity, in breast milk.

Methods: DMBT1 was detected in breast milk by Western blotting and its concentration was quantified by ELISA in 95 breast milk samples collected from mothers of preterm and term neonates during the first four weeks after delivery.