Publications by authors named "Sebastian Pinel"

Article Synopsis
  • The study investigated the inflammatory responses in patients undergoing transcatheter aortic valve implantation (TAVI) using low radial force valves versus high radial force valves.
  • It found that patients with low radial force valves had significantly lower levels of high-sensitivity C-reactive protein (hsCRP) after the procedure, indicating less inflammation.
  • Additionally, these patients experienced fewer occurrences of new left bundle branch block (LBBB), suggesting that lower inflammation might reduce the risk of heart conduction issues.
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Background: Interleukin-1 blockade with anakinra leads to a transient increase in eosinophil blood count (eosinophils) in patients with acute myocardial infarction. We aimed to investigate the effect of anakinra on changes in eosinophils in patients with heart failure (HF) and their correlation with cardiorespiratory fitness (CRF).

Methods: We measured eosinophils in 64 patients with HF (50% females), 55 (51-63) years of age, before and after treatment, and, in a subset of 41 patients, also after treatment cessation.

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