Publications by authors named "Sebastian Philipp von Hertzberg-Boelch"
Article Synopsis
- Cartilage repair techniques for hip chondral defects are vital in treating conditions like femoroacetabular impingement, especially in young patients, to prevent osteoarthritis progression.
- A study of 116,179 hip-preserving surgeries in Germany from 2006-2022 revealed that males underwent more procedures than females, with a trend towards minimally invasive arthroscopies over arthrotomies.
- The peak of these procedures occurred around 2013, particularly for arthroscopy; however, the numbers have declined, emphasizing the need for ongoing research into the effectiveness and cost benefits of regenerative techniques in younger patients.
Background: The formation of biofilms, characterized by cell aggregation and extracellular polymeric substance (EPS) production, is a common feature of periprosthetic joint infections (PJI).
Objective: The current study aimed to investigate the development of biofilm features in vitro within less than 3 weeks by Staphylococcus aureus isolated from PJIs.
Methods: Biofilms were grown on sandblasted titanium discs, and fluorescence spectroscopy and microscopy were used to observe biofilm maturation for 21 days.
Background: The use of polymethylmethacrylate cement for in-situ implant augmentation has considerable disadvantages: it is potentially cytotoxic, exothermic and non-degradable. Therefore, the primary aim of this study was to develop a magnesium phosphate cement which meets the requirements for in-situ implant augmentation as an alternative. Secondly, this experimental cement was compared to commercial bone cements in a biomechanical test set-up using augmented femoral head blades.
View Article and Find Full Text PDFThis literature review discusses the use of antibiotic loaded polymethylmethacrylate bone cements in arthroplasty. The clinically relevant differences that have to be considered when antibiotic loaded bone cements (ALBC) are used either for long-term implant fixation or as spacers for the treatment of periprosthetic joint infections are outlined. In this context, in vitro findings for antibiotic elution and material properties are summarized and transferred to clinical use.
View Article and Find Full Text PDFBackground: Joint aspiration with analysis of synovial fluid white blood cell count (WBC) and microbiological culture is a widely established aspect in the diagnosis of shoulder joint infections (SJI). In case of a two stage revision for SJI, joint aspiration before re-/implantation of a total shoulder arthroplasty (TSA) was used to rule out persistent infection for years but its value is under debate. Shoulder specific data on all aspects is rare.
View Article and Find Full Text PDFBackground: The diagnosis of periprosthetic shoulder infection (PSI) requires a thorough diagnostic workup. Synovial fluid aspiration has been proven to be a reliable tool in the diagnosis of joint infections of the lower extremity, but shoulder specific data is limited. This study defines a threshold for synovial fluid white blood cell count (WBC) and assesses the reliability of microbiological cultures.
View Article and Find Full Text PDFBackground: The primary aim of this study was to identify modifiable patient-related predictors of blood transfusions and perioperative complications in total hip and knee arthroplasty. Individual predictor-adjusted risks can be used to define preoperative treatment thresholds.
Methods: We performed this retrospective monocentric study in orthopaedic patients who underwent primary total knee or hip arthroplasty.
Article Synopsis
- This study examined the effects of topical tranexamic acid (TXA) on gentamicin release from bone cement used in total joint arthroplasty without increasing complications.
- Twelve bone cement cylinders were tested to compare the gentamicin release from those soaked in fetal calf serum alone versus those soaked in fetal calf serum with TXA over a week.
- Results showed no significant difference in gentamicin concentration, antimicrobial activity, or compressive strength between the two soaking conditions, indicating that TXA does not compromise antibiotic effectiveness.
Purpose: Patient-specific, flanged acetabular components are used for the treatment of Paprosky type III defects during revision total hip arthroplasty (THA). This monocentric retrospective cohort study analyzes the outcome of patients treated with custom made monoflanged acetabular components (CMACs) with intra- and extramedullary iliac fixation.
Methods: 14 patients were included who underwent revision THA with CMACs for the treatment of Paprosky type III defects.