Evolution of single-lead ECG for STEMI detection using a deep learning approach.

Background: While ST-Elevation Myocardial Infarction (STEMI) door-to-balloon times are often below 90 min, symptom to door times remain long at 2.5-h, due at least in part to a delay in diagnosis.

Objectives: To develop and validate a machine learning-guided algorithm which uses a single‑lead electrocardiogram (ECG) for STEMI detection to speed diagnosis.

Estimation of pure quantum states in high dimension at the limit of quantum accuracy through complex optimization and statistical inference.

Quantum tomography has become a key tool for the assessment of quantum states, processes, and devices. This drives the search for tomographic methods that achieve greater accuracy. In the case of mixed states of a single 2-dimensional quantum system adaptive methods have been recently introduced that achieve the theoretical accuracy limit deduced by Hayashi and Gill and Massar.