Publications by authors named "Sebastian Molina"
Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors.
Gabriel Rojas-Jiménez Daniela Solano Álvaro Segura Andrés Sánchez Stephanie Chaves-Araya Sebastián Molina
Front Med Technol
January 2022
Article Synopsis
- Vaccines are vital in fighting COVID-19 but may not work well for people with weakened immune systems, highlighting the need for alternative treatments like anti-SARS-CoV-2 immunoglobulins.
- A study compared two types of intravenous immunoglobulins: one made from vaccinated donors (VP-IVIg) and one from recovered COVID-19 patients (CP-IVIg), finding that VP-IVIg had higher concentrations of neutralizing antibodies.
- The research suggests that VP-IVIg is safe and effective, and using caprylic acid precipitation is a practical method to produce these treatments, especially beneficial for lower-income countries facing the pandemic.
Artificial membranes are models for biological systems and are important for applications. We introduce a dry two-step self-assembly method consisting of the high-vacuum evaporation of phospholipid molecules over silicon, followed by a subsequent annealing step in air. We evaporate dipalmitoylphosphatidylcholine (DPPC) molecules over bare silicon without the use of polymer cushions or solvents.
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