Background: Controversy exists regarding the impact of small for gestational age (SGA = birth weight < 10th percentile) status on mortality and major morbidities.
Aim: To assess the effects of SGA on mortality and major morbidities in ≤750 gram (g) neonates.
Study Design: Retrospective (01/2005-12/2017), single center study at a tertiary NICU.
Cerebellar granule cells (GCs) make up the majority of all neurons in the vertebrate brain, but heterogeneities among GCs and potential functional consequences are poorly understood. Here, we identified unexpected gradients in the biophysical properties of GCs in mice. GCs closer to the white matter (inner-zone GCs) had higher firing thresholds and could sustain firing with larger current inputs than GCs closer to the Purkinje cell layer (outer-zone GCs).
View Article and Find Full Text PDF