Publications by authors named "Sebastian Koller"
Menthyl Grignard reagent 1 from either menthyl chloride (2) or neomenthyl chloride (3) consists of menthylmagnesium chloride (1a), neomenthylmagnesium chloride (1b), trans- p-menthane (4), 2-menthene (8), 3-menthene (9), and Wurtz coupling products including symmetrical bimenthyl 13. The diastereomeric ratio 1a/1b was determined in situ by C NMR or after DO quenching by H NMR analysis. Hydrolysis of the C-Mg bond proceeds with retention of configuration at C-1.
View Article and Find Full Text PDFBackground: Optimal visualization of the operative field and methods that additionally provide supportive optical information form the basis for target-directed and successful surgery. This article strives to give an overview of current enhanced visualization techniques in visceral surgery and to highlight future developments.
Methods: The article was written as a comprehensive review on this topic and is based on a MEDLINE search and ongoing research from our own group and from other working groups.
Different components of the newly defined field of surgical data science have been under research at our groups for more than a decade now. In this paper, we describe our sensor-driven approaches to workflow recognition without the need for explicit models, and our current aim is to apply this knowledge to enable context-aware surgical assistance systems, such as a unified surgical display and robotic assistance systems. The methods we evaluated over time include dynamic time warping, hidden Markov models, random forests, and recently deep neural networks, specifically convolutional neural networks.
View Article and Find Full Text PDFArticle Synopsis
- Hospital antibiotic stewardship programs help control how antibiotics are prescribed, which can reduce infections caused by bacteria that don't respond to medicines.
- In a study, they focused on reducing the use of a specific medicine called daptomycin for certain infections and started testing the tissue around joint replacements to better diagnose infections.
- After the program started, the overall use of antibiotics went down a lot, and they saw a big drop in daptomycin use while also increasing the use of a different antibiotic called flucloxacillin.
Purpose: To investigate why natural orifice translumenal endoscopic surgery (NOTES) has not yet become widely accepted and to prove whether the main reason is still the lack of appropriate platforms due to the deficiency of applicable interfaces.
Methods: To assess expectations of a suitable interface design, we performed a survey on human-machine interfaces for NOTES mechatronic support systems among surgeons, gastroenterologists, and medical engineers. Of 120 distributed questionnaires, each consisting of 14 distinct questions, 100 (83%) were eligible for analysis.
Reliability of sensor-based real-time workflow recognition in laparoscopic cholecystectomy.
Int J Comput Assist Radiol Surg
November 2014
Purpose: Laparoscopic cholecystectomy is a very common minimally invasive surgical procedure that may be improved by autonomous or cooperative assistance support systems. Model-based surgery with a precise definition of distinct procedural tasks (PT) of the operation was implemented and tested to depict and analyze the process of this procedure.
Methods: Reliability of real-time workflow recognition in laparoscopic cholecystectomy ([Formula: see text] cases) was evaluated by continuous sensor-based data acquisition.