Publications by authors named "Sebastian Gaertner"

Article Synopsis
  • The study evaluated how well families in Bavaria, Germany, followed recommendations from the German society for sleep medicine to prevent sudden infant death syndrome (SIDS) during infant sleep.
  • Data was collected through interviews and questionnaires from a birth cohort at the University Children's Hospital Regensburg, tracking sleep settings, positions, and environmental factors from birth to 1 year.
  • Results showed that while most parents intended to follow guidelines, there was a significant gap in actual practices, with many infants sleeping in the parents' bed and some being placed in risky positions such as on their stomachs.
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Background: There are data on the safety of cancer surgery and the efficacy of preventive strategies on the prevention of postoperative symptomatic COVID-19 in these patients. But there is little such data for any elective surgery. The main objectives of this study were to examine the safety of bariatric surgery (BS) during the coronavirus disease 2019 (COVID-19) pandemic and to determine the efficacy of perioperative COVID-19 protective strategies on postoperative symptomatic COVID-19 rates.

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Single nucleotide polymorphisms (SNPs) close to the gain-of-function substitution, Asn(107)Ile (rs324981, A>T), in Neuropeptide S Receptor 1 (NPSR1) have been associated with asthma. Furthermore, a functional SNP (rs4751440, G>C) in Neuropeptide S (NPS) encodes a Val(6)Leu substitution on the mature peptide that results in reduced bioactivity. We sought to examine the effects of different combinations of these NPS and NPSR1 variants on downstream signaling and genetic risk of asthma.

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Background: Patients at the end of life often receive numerous medications for symptom management. In contrast to all other clinical situations, the aim of pharmacotherapy is strictly focused on quality of life.

Objective: The primary aims of this study were to assess the potential for drug-drug interactions (DDIs) in patients at the very end of life by identifying drug combinations and risk factors associated with a high risk of DDIs; and evaluate the clinical relevance of the potential DDIs in this unique patient population.

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