Publications by authors named "Sebastian C Diaz Velez"
Carbon-based quantum dots (CBQDs), sulfur-doped carbon-based quantum dots (S-CBQDs), and nitrogen-doped carbon-based quantum dots (N-CBQDs) have strong potential for drug delivery platforms. They were conjugated with andrographolide, a well-known hydrophobic drug, to study the concomitant changes in hydrophilicity. The interactions between these nanomaterials and the drug were studied by characterizing the optical and structural properties of the nanoparticles before and after coupling with the drug.
View Article and Find Full Text PDFCopper-Based Antibiotic Strategies: Exploring Applications in the Hospital Setting and the Targeting of Cu Regulatory Pathways and Current Drug Design Trends.
Aixa M Orta-Rivera Yazmary Meléndez-Contés Nataniel Medina-Berríos Adriana M Gómez-Cardona Andrés Ramos-Rodríguez
Inorganics (Basel)
June 2023
Article Synopsis
- - Classical antibacterial drugs were developed to target specific bacterial traits to minimize effects on human cells, but evolving bacteria and their resistance have created superbugs that first-line treatments can't effectively combat.
- - There is a pressing need for new antibacterial drugs, and this review explores the potential of using copper's toxicity against bacteria, as pathogenic strains have low tolerance for copper.
- - Research shows that using copper-containing materials in hospitals may reduce infections, and novel strategies targeting bacterial copper regulation could enhance treatment effectiveness, especially in combination with existing drugs.