Publications by authors named "Sebastian Brill"
Per- and polyfluoroalkyl substances (PFAS), often referred to as "forever chemicals", are a class of man-made, extremely stable chemicals, which are widely used in industrial and commercial applications. Exposure to some PFAS is now known to be detrimental to human health. By virtue of PFAS long residence times, they are widely detected in the environment, including remote locations such as the Arctics, where the origin of the PFAS is poorly understood.
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- - The war in Ukraine has prompted a shift in the German Armed Forces' focus toward national and alliance defense, highlighting the need for improved medical and surgical responses to conventional warfare injuries.
- - A literature review identified severe traumatic brain injuries and thoracoabdominal hemorrhage as the leading causes of primary mortality in war injuries, with burns and neck injuries contributing significantly to secondary mortality.
- - To reduce mortality in modern warfare, controlling thoracoabdominal hemorrhage is crucial, and the German Armed Forces hospitals should prioritize treatments for traumatic brain injuries, burns, and neck injuries.
Soldiers regularly participate in missions abroad and subjectively adapt to this situation. However, they have an increased lifetime cardiovascular risk compared to other occupational groups. To test the hypothesis that foreign deployment results in different stress habituation patterns, we investigated long-term psychological and bio-physiological stress responses to a repeated social stress task in healthy soldiers with and without foreign deployment.
View Article and Find Full Text PDFAccumulation of stress is a prognostic trigger for cardiovascular disease. Classical scores for cardiovascular risk estimation typically do not consider psychosocial stress. The aim of this study was to develop a global stress index (GSI) from healthy participants by combining individual measures of acute and chronic stress from childhood to adult life.
View Article and Find Full Text PDFPsychosocial stress increases cardiovascular risk, which coincides with enhanced oxidative DNA damage. Increased sympathetic tone-related catecholamine release causes oxidative stress, which contributes to catecholamine-related cardiotoxicity. Therefore, we tested the hypothesis whether acute psychosocial stress induces oxidative DNA damage, its degree being related to the cardiovascular risk profile and depending on the sympathetic stress response.
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- The article reviews various diagnostic methods used for diagnosing blunt abdominal trauma, including physical exams, imaging techniques, and lab tests.
- It highlights that multislice computed tomography (MSCT) is the most effective method with high sensitivity and specificity, while other methods like ultrasound and lab values provide additional context for patient evaluation.
- The authors propose a diagnostic algorithm based on their literature review and findings, emphasizing the need to interpret clinical and imaging data together for optimal treatment planning.