Time separation technique: Accurate solution for 4D C-Arm-CT perfusion imaging using a temporal decomposition model.

Purpose: The issue of perfusion imaging using a temporal decomposition model is to enable the reconstruction of undersampled measurements acquired with a slowly rotating x-ray-based imaging system, for example, a C-arm-based cone beam computed tomography (CB-CT). The aim of this work is to integrate prior knowledge into the dynamic CT task in order to reduce the required number of views and the computational effort as well as to save dose. The prior knowledge comprises of a mathematical model and clinical perfusion data.