Publications by authors named "Sebastiaan Lootens"
Atrial Topology for a Unified Understanding of Typical and Atypical Flutter.
Mattias Duytschaever Robin Van den Abeele Niels Carlier Arthur Santos Bezerra Bjorn Verstraeten Sebastiaan Lootens
Circ Arrhythm Electrophysiol
November 2024
Article Synopsis
- Macroreentry is the main cause of typical and atypical flutter, but many questions about it remain unanswered, prompting a study that uses topology to investigate atrial tachycardia activation patterns.
- Researchers utilized a computational model resembling a closed sphere with holes to analyze cases of tachycardia, focusing on activation maps and ablation responses in 131 clinical cases.
- The study's findings suggest that reentrant activity on closed surfaces consistently shows paired rotation, and through mathematical principles, they established a framework to better understand flutter and its treatment outcomes.
Cardiac arrhythmias such as atrial fibrillation (AF) are recognised to be associated with re-entry or rotors. A rotor is a wave of excitation in the cardiac tissue that wraps around its refractory tail, causing faster-than-normal periodic excitation. The detection of rotor centres is of crucial importance in guiding ablation strategies for the treatment of arrhythmia.
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