Publications by authors named "Sebastiaan L Meyer Viol"

Background: With the introduction of prostate specific membrane antigen (PSMA) PET/CT, the detection rate of prostate cancer metastases has improved significantly, both for primary staging and for biochemical recurrence. EANM/SNMMI guidelines recommend a 60 min time interval between [ Ga]Ga-PSMA administration and acquisition.

Purpose: This study evaluates the possibility of a shorter time interval by investigating the dynamic change in image quality measures.

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Article Synopsis
  • [F]mFBG is a special type of imaging test that helps doctors see tumors in kids with a disease called neuroblastoma.
  • In a study with 14 young patients, two different imaging methods ([I]mIBG and [F]mFBG) were compared to see which one found more tumors.
  • The study showed that [F]mFBG found more tumors and was quicker to perform, making it a promising option for doctors to help in treating neuroblastoma.
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Background: Personalized molecular radiotherapy based on theragnostics requires accurate quantification of the amount of radiopharmaceutical activity administered to patients both in diagnostic and therapeutic applications. This international multi-center study aims to investigate the clinical measurement accuracy of radionuclide calibrators for 7 radionuclides used in theragnostics: Tc, In, I, I, I, Lu, and Y.

Methods: In total, 32 radionuclide calibrators from 8 hospitals located in the Netherlands, Belgium, and Germany were tested.

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Background: Quantitative SPECT imaging in targeted radionuclide therapy with lutetium-177 holds great potential for individualized treatment based on dose assessment. The establishment of dose-effect relations requires a standardized method for SPECT quantification. The purpose of this multi-center study is to evaluate quantitative accuracy and inter-system variations of different SPECT/CT systems with corresponding commercially available quantitative reconstruction algorithms.

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