Publications by authors named "Seaone Choi"
Front Microbiol
October 2023
Article Synopsis
- This study investigates the distribution of malonate semialdehyde decarboxylases (MSADs) in mycobacterial species by analyzing the genomes of 192 reference strains.
- It was found that MSAD-1 and MSAD-2 are present in about 45.3% of those strains, but many high-virulence strains, notably pathogenic mycobacteria, lack these genes, indicating potential gene loss.
- Further analysis of 255 strains from specific subspecies revealed only 47.4% had MSADs, with some showing mutations, suggesting that MSADs may play a role in mycobacterial evolution and pathogenesis, warranting future research.
