Publications by authors named "Sean-Paul Gerard Williams"

Meniscal tears are one of the most frequent injuries to the knee, with an estimated incidence of 222 per 100,000 individuals aged 18 to 55 years based on magnetic resonance imaging. Poor outcomes following meniscal surgical interventions are common and have led many surgeons to use biologic augmentation strategies to enhance the healing. We conducted a single-center, retrospective, observational study of patients who underwent arthroscopic meniscectomy with and without adjunctive platelet-rich plasma (PRP) or the particulate form of amniotic umbilical cord (AMUC) tissue.

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An osteochondral defect in the hip can be a painful and limiting pathologic process. The damaged joint may progress into premature osteoarthritis, further limiting a patient's functionality. A 24-year-old male presented to the clinic with left hip pain.

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Purpose: Viable cartilage allograft (VCA) is a cartilage tissue matrix that contains cryopreserved viable allogeneic cartilage fibres. This study aimed to assess safety and benefits in treating focal knee cartilage defects with VCA. We hypothesized that VCA is a safe single-stage procedure in isolated chondral defects.

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Article Synopsis
  • Tears of the gluteus medius and minimus muscles are frequently blamed for chronic lateral hip pain in middle-aged people, often resulting from long-term degeneration.
  • A rare case of an acute tear in a 78-year-old male marathon runner led to unsuccessful conservative treatment, prompting him to undergo surgery, which ultimately allowed him to return to his normal activities.
  • Chronic injuries are more common than acute ones, with patients often misdiagnosed due to vague symptoms, including gradual lateral hip pain that worsens with certain movements.
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Background: Patellofemoral arthritis is a common cause of anterior knee pain and limits flexion-related activities of daily living and exercise. While frequently present in bicompartmental and tricompartmental osteoarthritis, patellofemoral arthritis can occur in isolation. Patellofemoral arthroplasty as a treatment option is gaining in popularity, especially with new implant designs.

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Purpose: To determine whether postoperative cardiac complications following orthopaedic trauma treatment are associated with longer lengths of stay.

Methods: This was a retrospective cohort study. We analyzed orthopaedic trauma patients in the United States for whom data was collected in the ACS-NSQIP database between the years of 2006 and 2013.

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Inhibition of the extracellular process of collagen fibril formation represents a new approach to limiting posttraumatic or postsurgical localized fibrosis. It has been demonstrated that employing a monoclonal antibody that targets the C-terminal telopeptide of the α2 chain of collagen I blocks critical collagen I-collagen I interaction, thereby reducing the amount of collagen deposits in vitro and in animal models. Here, we developed a chimeric variant of a prototypic inhibitory antibody of mouse origin.

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Angiosarcoma of the femoral artery is an extremely rare malignant vascular tumor. The initial diagnosis is difficult to establish and distal metastasis can sometimes be the only presenting symptom. In this paper, we report the case of a 54-year-old man who presented with multiple painful necrotic lesions over the right foot secondary to an intimal angiosarcoma of the right common femoral artery.

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Introduction And Aims: Tobacco use and heavy alcohol consumption are associated with increased morbidity and mortality. There is limited research on the correlation between tobacco and risky levels of alcohol use and the possible complications associated with a hospital admission. The underestimation of problem drinking, in particular, has obvious repercussions for the management of patients in hospital.

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A 60-year-old man presented with ureteric obstruction secondary to a mycotic right common iliac artery aneurysm complicating methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. The diagnosis of MRSA was not known at the time of surgery, and in situ replacement of the aneurysm using a rifampicin-bonded prosthesis was performed. The patient made a full recovery, and to date there is no evidence of residual or recurrent infection.

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