Publications by authors named "Sean W Riley"
Mol Pharmacol
January 2016
Article Synopsis
- The study focuses on G protein-coupled receptors for sphingosine 1-phosphate (S1P), particularly the S1P3 receptor, which plays a crucial role in regulating heart rhythm.
- A new antagonist, SPM-354, was found effective in reversing issues like complete heart block and bradycardia in mouse models, indicating its potential therapeutic value.
- The research suggests that S1P3 is located in key areas of the heart's conduction system, highlighting its importance in understanding cardiac health and potential treatments for heart conditions.
