Publications by authors named "Sean T Osis"

Article Synopsis
  • Quantitative biomechanical gait analysis is crucial for diagnosing and treating injuries and diseases, but there is a need for standardized benchmark datasets as these labs often function in isolation.
  • To fill this gap, an open biomechanics dataset has been created, featuring data from 1798 healthy and injured participants of various ages walking and running on a treadmill.
  • The dataset, available on Figshare+, includes raw data, metadata, and tutorials on analyzing the data, covering topics from basic file loading to advanced statistical methods like principal component analysis and clustering.
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Article Synopsis
  • The study examines how extrinsic and intrinsic factors contribute to running-related injuries, focusing on kinematic differences between higher- and lower-mileage runners.
  • Participants were divided into higher-mileage (≥32 km/week) and lower-mileage (≤25 km/week) groups, with 3D kinematic data collected during running.
  • The results showed high accuracy in classifying runners by mileage (92.59% overall, 89.83% for females, and 100% for males), indicating that mileage and gender significantly influence running biomechanics.
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The objective of this study was to determine whether subject-specific or group-based models provided better classification accuracy to identify changes in biomechanical running gait patterns across different inclination conditions. The classification process was based on measurements from a single wearable sensor using a total of 41,780 strides from eleven recreational runners while running in real-world and uncontrolled environment. Biomechanical variables included pelvic drop, ground contact time, braking, vertical oscillation of pelvis, pelvic rotation, and cadence were recorded during running on three inclination grades: downhill, -2° to -7°; level, -0.

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Article Synopsis
  • Running-related overuse injuries can be influenced by both intrinsic (like biomechanics) and extrinsic (like weather) factors, but how weather impacts running gait is not well understood.
  • This study aimed to create a classification model to analyze changes in running biomechanics in different weather conditions using wearable sensors, recording data during winter and spring.
  • The findings showed that a random forest machine learning algorithm could effectively classify running patterns and predict variations in individual runners' biomechanics, achieving high accuracy rates in distinguishing between different environmental conditions.
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The purpose of this study was to classify runners in sex-specific groups as either competitive or recreational based on center of mass (CoM) accelerations. Forty-one runners participated in the study (25 male and 16 female), and were labeled as competitive or recreational based on age, sex, and race performance. Three-dimensional acceleration data were collected during a 5-minute treadmill run, and 24 features were extracted.

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Article Synopsis
  • The study aimed to identify distinct sub-groups of gait patterns in runners with patellofemoral pain (PFP) using pelvic acceleration data, which is easier to collect and less error-prone compared to traditional 3D kinematic data.
  • The researchers conducted a hierarchical cluster analysis on 110 PFP subjects, finding two different running sub-groups among females, while males did not form distinct clusters.
  • Significant differences in pelvic acceleration and lower limb kinematics were observed between the identified female clusters and between males and females, indicating variability in running patterns and potential implications for treatment.
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The increasing amount of data in biomechanics research has greatly increased the importance of developing advanced multivariate analysis and machine learning techniques, which are better able to handle "big data". Consequently, advances in data science methods will expand the knowledge for testing new hypotheses about biomechanical risk factors associated with walking and running gait-related musculoskeletal injury. This paper begins with a brief introduction to an automated three-dimensional (3D) biomechanical gait data collection system: 3D GAIT, followed by how the studies in the field of gait biomechanics fit the quantities in the 5 V's definition of big data: volume, velocity, variety, veracity, and value.

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Accelerometers have been used to classify running patterns, but classification accuracy and computational load depends on signal segmentation and feature extraction. Stride-based segmentation relies on identifying gait events, a step avoided by using window-based segmentation. For each segment, discrete points can be extracted from the accelerometer signal, or advanced features can be computed.

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Marker placement deviation has been shown to be the largest source of error in gait kinematic data, limiting the ability of clinicians and researchers to conduct between-day or between-center investigations. Prior marker-placement standardization methods are either impractical for a clinical setting or rely on expert marker placement. However, a recently developed, real-time feedback tool has been developed and shown to improve marker placement and downstream kinematic calculations.

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Background: Muscle strengthening exercises consistently demonstrate improvements in the pain and function of adults with knee osteoarthritis, but individual response rates can vary greatly. Identifying individuals who are more likely to respond is important in developing more efficient rehabilitation programs for knee osteoarthritis. Therefore, the purpose of this study was to determine if pre-intervention multi-sensor accelerometer data (e.

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Article Synopsis
  • An expert system was created to enhance the reliability of marker-based gait analysis for examiners.
  • The study evaluated how effective this feedback tool was in improving gait analysis for individuals with lower limb osteoarthritis.
  • Results showed that using the feedback tool led to better reliability in the data collected during the three-dimensional gait analysis of 27 individuals.
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Certain homogeneous running subgroups demonstrate distinct kinematic patterns in running; however, the running mechanics of competitive and recreational runners are not well understood. Therefore, the purpose of this study was to determine whether we could separate and classify competitive and recreational runners according to gait kinematics using multivariate analyses and a machine learning approach. Participants were allocated to the 'competitive' (n = 20) or 'recreational' group (n = 15) based on age, sex, and recent race performance.

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The aim of this study was to determine the test-retest reliability of linear acceleration waveforms collected at the low back, thigh, shank, and foot during walking, in a cohort of knee osteoarthritis patients, by applying two separate sensor attitude correction methods (static attitude correction and dynamic attitude correction). Linear acceleration data were collected on the subjects׳ most affected limb during treadmill walking on two separate days. Results reveal all attitude corrected acceleration waveforms displayed high repeatability, with coefficient of multiple determination values ranging from 0.

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Article Synopsis
  • Modern data science methods enhance fields like computer vision and economics by providing new insights from complex datasets, complementing traditional experimental approaches.
  • The article discusses how incorporating data science can improve understanding of gait biomechanics and treatment planning in this area.
  • It highlights challenges such as the need for new tools, better data-sharing infrastructure, and interdisciplinary education to effectively implement data science in clinical gait analysis and biomechanics research.
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An ongoing challenge in the application of gait analysis to clinical settings is the standardized detection of temporal events, with unobtrusive and cost-effective equipment, for a wide range of gait types. The purpose of the current study was to investigate a targeted machine learning approach for the prediction of timing for foot strike (or initial contact) and toe-off, using only kinematics for walking, forefoot running, and heel-toe running. Data were categorized by gait type and split into a training set (∼30%) and a validation set (∼70%).

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Background: Females have a two-fold risk of developing knee osteoarthritis (OA) as compared to their male counterparts and atypical walking gait biomechanics are also considered a factor in the aetiology of knee OA. However, few studies have investigated sex-related differences in walking mechanics for patients with knee OA and of those, conflicting results have been reported. Therefore, this study was designed to examine the differences in gait kinematics (1) between male and female subjects with and without knee OA and (2) between healthy gender-matched subjects as compared with their OA counterparts.

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Background: Mild-to-moderate hip osteoarthritis is often managed clinically in a non-surgical manner. Effective non-surgical management of this population requires characterizing the specific impairments within this group. To date, a complete description of all lower extremity kinematics in mild-to-moderate hip osteoarthritis patients has not been presented.

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In order to provide effective test-retest and pooling of information from clinical gait analyses, it is critical to ensure that the data produced are as reliable as possible. Furthermore, it has been shown that anatomical marker placement is the largest source of inter-examiner variance in gait analyses. However, the effects of specific, known deviations in marker placement on calculated kinematic variables are unclear, and there is currently no mechanism to provide location-based feedback regarding placement consistency.

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Objective: Muscle strengthening exercises have been shown to improve pain and function in adults with mild-to-moderate knee osteoarthritis, but individual response rates can vary greatly. Predicting individuals who respond and those who do not is important in developing a more efficient and effective model of care for knee osteoarthritis (OA). Therefore, the purpose of this study was to use pre-intervention gait kinematics and patient-reported outcome measures to predict post-intervention response to a 6-week hip strengthening exercise intervention in patients with mild-to-moderate knee OA.

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Female runners have a two-fold risk of sustaining certain running-related injuries as compared to their male counterparts. Thus, a comprehensive understanding of the sex-related differences in running kinematics is necessary. However, previous studies have either used discrete time point variables and inferential statistics and/or relatively small subject numbers.

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As 3-dimensional (3D) motion-capture for clinical gait analysis continues to evolve, new methods must be developed to improve the detection of gait cycle events based on kinematic data. Recently, the application of principal component analysis (PCA) to gait data has shown promise in detecting important biomechanical features. Therefore, the purpose of this study was to define a new foot strike detection method for a continuum of striking techniques, by applying PCA to joint angle waveforms.

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Accelerometers are increasingly used tools for gait analysis, but there remains a lack of research on their application to running and their ability to classify running patterns. The purpose of this study was to conduct an exploratory examination into the capability of a tri-axial accelerometer to classify runners of different training backgrounds and experience levels, according to their 3-dimensional (3D) accelerometer data patterns. Training background was examined with 14 competitive soccer players and 12 experienced marathon runners, and experience level was examined with 16 first-time and the same 12 experienced marathon runners.

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As biomechanical research evolves, a continuing challenge is the standardization of data collection and analysis techniques. In gait analysis, placement of markers to construct an anatomical model has been identified as the single greatest source of error; however, there is currently no standardized approach to quantifying these errors. The current study applies morphometric methods, including a generalized Procrustes analysis (GPA) and a nearest neighbour comparison to quantify discrepancies in marker placement, with the goal of improving reliability in gait analysis.

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Objective: The objective of this study is to examine ground kinetics early in stance while walking on a contaminated surface and assess the potential of kinetics to quantify risk of slipping.

Background: Prior studies of slipping have dismissed early ground kinetic data,and therefore no prior literature has been able to assess the viability of using these data to quantify slip potential.

Method: A total of 11 healthy male participants volunteered to walk over a force plate that was at random times contaminated with soap.

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The influence of golf club stiffness on driving performance is currently unclear, and it is possible that this ambiguity is due in part to golfer adaptation to equipment. The purpose of the current study was to elucidate mechanisms of adaptation to club stiffness, during the golf swing, by employing tendon vibration to distort proprioceptive feedback. Vibration (∼50 Hz, ∼1 mm amplitude) was applied to the upper extremities of 24 golfers using DC motors with eccentric weights.

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