Publications by authors named "Sean R G Duffy"

Objective: To investigate the effect of the introduction of nurse hysteroscopists on patient satisfaction at an outpatient hysteroscopy clinic in the United Kingdom.

Methods: Satisfaction with outpatient hysteroscopy performed in a University Teaching Hospital was measured using an anonymous structured questionnaire in 2000 and 2005. The unpaired t test, Mann-Whitney U test, or chi(2) test was used depending on the level of measurement.

View Article and Find Full Text PDF

Study Objectives: To build a simple in vitro uterine perfusion model for investigating the clinical effectiveness of endometrial ablation.

Design: Comparative laboratory and in vivo study (Canadian Task Force classification II-2).

Setting: University teaching hospital.

View Article and Find Full Text PDF

Study Objective: To determine the effect of a 9-mm diameter carbon dioxide cryoprobe, the Endocryo, on myomas and endometrial/myometrial tissue in vitro.

Design: Comparative laboratory study (Canadian Task Force classification II-2).

Setting: University laboratory.

View Article and Find Full Text PDF

Objective: This study was undertaken to assess baseline endometrial molecular events in the ATAC (Arimidex, tamoxifen, alone, or in combination) trial of breast cancer adjuvant therapy.

Study Design: Estrogen receptor (ER) and progesterone receptor (PR) levels and markers of cell proliferation (Ki67) and apoptosis ( Bcl -2) were assessed in 93 patients at baseline.

Results: An inactive/atrophic endometrium was found in 63 patients, 5 had a proliferative endometrium, and 12 had a secretory endometrium.

View Article and Find Full Text PDF

Objective: To obtain a greater understanding of the pathogenesis of endometrial polyps and to gain insight into which factors play a pivotal role in their growth.

Design: Retrospective analysis of archived paraffin-embedded specimens.

Setting: St James's University Hospital.

View Article and Find Full Text PDF