Understanding the track and field sprint start through a functional analysis of the external force features which contribute to higher levels of block phase performance.

This study aimed to identify the continuous ground reaction force (GRF) features which contribute to higher levels of block phase performance. Twenty-three sprint-trained athletes completed starts from their preferred settings during which GRFs were recorded separately under each block. Continuous features of the magnitude and direction of the resultant GRF signals which explained 90% of the variation between the sprinters were identified.

Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array.

Proteomics analysis of biofluid-derived vesicles holds enormous potential for discovering non-invasive disease markers. Obtaining vesicles of sufficient quality and quantity for profiling studies has, however, been a major problem, as samples are often replete with co-isolated material that can interfere with the identification of genuine low abundance, vesicle components. Here, we used a combination of ultracentrifugation and size-exclusion chromatography to isolate and analyse vesicles of plasma or urine origin.