Publications by authors named "Sean Inzerillo"
Neurospine
September 2024
Article Synopsis
- Minimally invasive spine surgery (MISS) reduces tissue damage through small incisions and advanced techniques, leading to benefits like less blood loss and shorter hospital stays compared to traditional open surgery.
- * A systematic review of literature from Jan 2013 to Mar 2024 analyzed complications related to MISS, finding that various complications (like nerve injuries and cerebrospinal fluid leaks) depend on the specific surgical approach (cervical, thoracic, or lumbar).
- * Although MISS generally lowers the risk of anatomical disruption, certain complications can still occur; the use of intraoperative monitoring and advanced technology may reduce these risks further, establishing MISS as a safe alternative to open surgery.
Article Synopsis
- This pilot study explores how using monetary incentives via an app can help improve patients' adherence to important preoperative and postoperative instructions.
- Conducted at Maimonides Medical Center, participants received rewards for completing specific health-related tasks through the TheraPay Rewards app, targeting both English and Spanish speakers.
- The results showed high adherence rates for preoperative tasks (about 98.7%), but significantly lower rates for postoperative tasks (around 60%), indicating the potential of financial incentives while also noting the need for improved support post-surgery.
Front Med (Lausanne)
May 2022
Article Synopsis
- The pandemic negatively impacted the care for patients with rheumatic diseases, leading to access difficulties and psychologically affecting their quality of life.
- A survey comparing patient and provider experiences with telemedicine was conducted in 2020 and 2021, revealing increased patient satisfaction and comfort with telemedicine services, while providers had mixed feelings about its effectiveness compared to in-person visits.
- Overall, while patients showed a strong preference for telemedicine and reported similar quality of life as pre-pandemic levels, the difference in satisfaction between patients and providers raises questions about the viability of telemedicine as a long-term alternative to traditional care.
Curr Rheumatol Rep
November 2021
Article Synopsis
- * Findings show that patients with SLE have a weaker immune response to vaccines compared to healthy individuals and that certain immunosuppressive medications may reduce vaccine effectiveness, but they don’t increase the risk of disease flare-ups or side effects.
- * The overall safety of COVID-19 vaccines for AIIRD patients is confirmed, and the benefits of vaccination are considered to significantly outweigh the risks; further research is needed on booster doses and managing immunosuppressant treatments around vaccination.
Trends Microbiol
March 2022
Article Synopsis
- - Glycans, which are sugar molecules found on the surfaces of cells, play crucial roles in how bacteria interact with their hosts, affecting both bacterial colonization and the immune responses of the host.
- - The review covers three main topics: the role of bacterial glycans in pathogenesis, the use of host glycans by bacteria, and the involvement of both in immune responses.
- - It highlights future directions for research in glycoscience, including the development of new antibacterial strategies to combat drug-resistant pathogens.
Article Synopsis
- * The study involved modifying and comparing the effectiveness of different monoclonal antibodies against CR- sequence type 258 (ST258), with findings indicating that murine IgG (mIgG) had superior binding, agglutination, and bactericidal activity compared to other antibody forms.
- * Results suggest that mIgG could be a viable adjunctive therapy for neutropenic patients at high risk for CR- infections, highlighting its potential role in addressing the urgent public health threat posed by antibiotic resistance.
