Design and validation of a thermoreversible material for percutaneous tissue hydrodissection.

Interventional oncology procedures such as thermal ablation are becoming routine for many cancers. Hydrodissection-separating tissues with fluids-protects tissues near the treatment zone to improve ablation's safety and facilitate more aggressive treatments. However, currently used fluids such as normal saline and 5% dextrose in water (D5W) migrate in the peritoneum, reducing their protective efficacy.