Publications by authors named "Sean D O'Broin"
Background: Efforts to improve maternal nutrition during pregnancy prompted an observational study of the occurrence of maternal iron deficiency and its laboratory diagnosis in almost 500 pregnancies.
Methods: In this longitudinal study, the biochemical and haematological iron indices of women (n=492) attending a prenatal clinic in a Dublin maternity hospital were assessed at first booking (mean 15.9 weeks), and after 24 weeks, and 36 weeks of gestation.
Background: A newly developed dried serum spot (DSS) vitamin B(12) assay compares well with a conventional reference serum vitamin B(12) microbiological assay (r=0.97, n=161) and demonstrates adequate within (CV% <6) and between assay (CV% <10) reproducibility.
Methods: The consistency of long-term vitamin B(12) assay performance was supported and validated using a reconstituted International Reference Serum (IRR 81/563) stored at -70 degrees C as both whole serum aliquots and as DSS.