Safety and efficacy of a nitrous oxide procedural sedation programme in a paediatric emergency department: a decade of outcomes.

Background: Nitrous oxide (NO) has multiple benefits in paediatric procedural sedation (PPS), but use is restricted by its limited analgesic properties. Analgesic potency could be increased by combining NO and intranasal fentanyl (INF). We assessed safety and efficacy data from 10 years (2011-2021) of our NO PPS programme.