Publications by authors named "Seamus C O'Brien"
Microorganisms
October 2021
Article Synopsis
- * Researchers isolated a novel bacteriophage (vB_PmiS_PM-CJR) that showed promise in breaking down these biofilms due to its depolymerase activity, which helps in degrading the biofilm structure.
- * The isolated tail spike protein from the bacteriophage was tested and found to significantly reduce bacterial adherence, indicating its potential as a new treatment strategy for catheter-associated infections.
Trends Biotechnol
April 2020
Article Synopsis
- * A healthy gut microbiome plays a crucial role in protecting against AMR, but antibiotic treatments can disrupt this balance, leading to dysbiosis and decreased diversity.
- * The review discusses new strategies for antibiotic delivery, such as avoiding effects on the gut microbiome and using targeted methods, that could help mitigate AMR issues.
