Publications by authors named "Se-Hoon Jang"

We developed inverted red quantum dot light-emitting diodes (QLEDs) with ZnO nanoparticles synthesized in open and closed systems. Wurtzite-structured ZnO nanoparticles were synthesized using potassium hydroxide and zinc acetate dihydrate at various temperatures in the open and closed systems. The particle size increases with increasing synthesis temperature.

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Objective: Atopic dermatitis (AD) is a chronic inflammatory skin disease that may be linked to changes in the gut microbiome. Acupuncture has been proven to be effective in reducing AD symptoms without serious adverse events, but its underlying mechanism is not completely understood. The purpose of this study was to investigate whether the potential effect of acupuncture on AD is gut microbiota-dependent.

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  • Respiratory exposure to particulate matter, particularly fine particulate matter (PM2.5) and diesel exhaust, leads to oxidative stress and inflammation in the lungs, increasing the risk of cardiovascular diseases.
  • The study investigated the effects of Securiniga suffruticosa (S. suffruticosa) on lung and cardiovascular inflammation induced by diesel exhaust particulate (DEP) in mice, finding that S. suffruticosa significantly reduced various inflammatory markers in the lungs and thoracic aorta.
  • The results suggested that S. suffruticosa may offer therapeutic benefits by lowering inflammation and oxidative stress in air pollution-exposed tissues by suppressing the NLRP3 signaling pathway.
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  • Safflower (L.) has historical uses in treating vascular issues related to the heart, brain, and diabetes, and this study explores its potential in reducing vascular inflammation in human cells.
  • The ethanol extract of safflower (ECT) was found to lower the adhesion of leukocytes and reduce key cell adhesion molecules, indicating a protective effect on blood vessel health.
  • ECT also decreases oxidative stress and suppresses harmful signaling pathways, suggesting it could be a promising natural treatment for vascular inflammation, but more research is needed to identify the most effective compounds.
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  • Renal ischemia-reperfusion (I/R) injury is a significant cause of acute renal failure, and the study investigates the effects of Geumgwe-sinkihwan (GSH), a traditional Chinese medicine, on a mouse model of this condition.
  • The experiment involved administering different doses of GSH to mice after inducing I/R injury through surgical clamping of renal arteries, revealing that GSH improves kidney function and reduces markers of renal injury.
  • The results showed that GSH decreases inflammatory cytokines and inflammasome-related proteins, suggesting its potential as a therapeutic agent to mitigate renal damage and inflammation in cases of acute renal failure.
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