Treatment of stage I non-small cell lung cancer with CyberKnife, image-guided robotic stereotactic radiosurgery.

The object of our study was to evaluate the clinical characteristics and outcomes of patients with stage I non-small cell lung cancer (NSCLC) who underwent radiosurgery using the CyberKnife, a newly developed technology to deliver radiation from multiple angles with a real-time target tracking system. A retrospective analysis of eight patients with stage I NSCLC who were treated with curative intent using the CyberKnife between 2002 and 2007 at a cancer center in Korea was performed. Among eight patients (seven men and one woman), three patients were ineligible for surgery due to poor lung function while four patients refused surgical treatment.

Esophageal and laryngeal cancer incidentally found on [18F]fluorodeoxyglucose positron emission tomography/computed tomography during the staging workup for lung cancer.

During staging workup for lung cancer of a 74-year-old man, 2 more incidental tumors were found on [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT). The 3 sites with cancer in this patient involved organs in which field cancerization has often been described, suggesting that triple primary tumors were more probable than metastasis. After treating them separately, complete response was achieved and sustained for > 2 years.