Publications by authors named "Scrobogna S"

This study reports the immunoelectrophoretic analysis performed on 95 samples of urinary proteins. This analysis shows that in the majority of cases the migrant proteins in gamma position are F(ab) and Fc fragments, and free light chains with a molecular weight between 70,000 and 10,000. There is evidence of an increase in the immunoglobulinic fragments during inflammatory processes and their disappearance afterwards.

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A report is given about the synthesis of IgG immunoglobulins in the pleural infiltrations. The quantity of immunoglobulins locally yielded is estimated through the ratio IgG/Albumin in the blood and in the infiltration. Evidence is given that the mechanic and neoplastic transudates are easily detectable on account of the failed local synthesis of immunoglobulins of IgG type.

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A report is given about the opportunity and the advantages of combining the traditional scheme for the study of the pathological immunoglobulins with the analysis of the uncoupling of the bow of precipitation against IgG and the isolation of the pathological immunoglobulin through a diluition of the serum such as to bring the fraction electrophoretically dispersed to not detectable levels and make it detectable the monoclonae portion electrophoretically homogeneous.

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The pleural fluids of 40 patients have been examined. Out of 15 cases of pulmonary cancer the presence of the secretory piece has been noted in 10 cases and its absence in the remaining 25 cases of nonneoplastic pathogenesis. Through the bidimensional immunoelectrophoresis the presence both of a slow IgA fraction (L) and of a fast one (V) has been noted.

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A simple technique of electroimmunodiffusion is described, which is fit for identifying the variations in the ratio IgG/Albumin in the spinal fluid (liquor). Furthermore a general scheme for the survey of the proteic situation in the spinal fluid is also proposed.

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Synthesis of a study of the proteins outline of the bronchial secretion with the qualitative and quantitative determination of six protein fractions (albumin, Alfa-antitrypsin, acid Alfa-glycoprotein, haptoglobin, transferrin); comparation of the concentration of these fractions of the expectoration with those of the serum of the patient himself.

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Study of the relationships between the variations of the connections between the components of the bronchial secretion and the viscosity of the sputum, with particular regard to the role of the IgA IIS and to the secretory piece.

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