Publications by authors named "Scott-Eugene Saverot"
Article Synopsis
- Hepatic fibrosis is caused by inflammation and healing processes that lead to liver dysfunction, involving various liver cells like hepatocytes and hepatic stellate cells.
- This study developed a 3D liver model with detachable polyelectrolyte multilayers (PEMs) that mimic the liver's mechanical environment, demonstrating that different mechanical properties affect the behavior of hepatic cells.
- Results showed that cells in mechanically varied environments displayed significant differences in proliferation and gene expression, highlighting the potential for these models to study liver fibrosis and cell behavior.
Gold-gold sulfide nanoparticles are of interest for drug delivery, biomedical imaging, and photothermal therapy applications due to a facile synthesis method resulting in small particles with high near-infrared (NIR) absorption efficiency. Previous studies suggest that the NIR sensitivity of these nanoparticles was due to hexagonally shaped metal-coated dielectric nanoparticles that consist of a gold sulfide core and gold shell. Here, we illustrate that the conventional synthesis procedure results in the formation of polydisperse samples of icosahedral gold particles, gold nanoplates, and small gold spheres.
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