A Prospective Open-Label Study for Treatment of Infraorbital Hollows Using a Volumizing Hyaluronic Acid Filler.

This study aimed to prospectively evaluate the effectiveness, patient satisfaction, and early adverse events of using the hyaluronic acid filler VYC-20L for the treatment of infraorbital hollowing. A total of 21 participants underwent injection of VYC-20L. FACE-Q satisfaction surveys before and after treatment along with early adverse events surveys were conducted.

Psychological distress, attitudes toward seeking help, and utilization of college counseling at a predominantly minority college.

Objective: This study examined psychological distress among students at a predominantly-minority college, attitudes toward seeking help, and utilization of college counseling services. Demographic variables and associations between 8 problem areas (depression, generalized anxiety, social anxiety, academic stress, eating concerns, family distress, hostility, substance use) were explored.

Participants: Participants were 347 students at a large public university.

Incorporating Fat Grafting with Facelift Surgery: When, How, and Where.

Facial aging is a multifactorial process with many articles over decades supporting various theories of varying causes. It is generally thought that aging occurs as a combination of changes in skin quality, gravitational descent of tissue with interaction of retaining ligaments on the ptotic tissue, and facial volume loss or the appearance of volume loss. The most significant cause of volume loss is skeletal remodeling and bone loss, which manifests as characteristic shadows and hollows on the face in conjunction with soft tissue changes that are yet to be completely elucidated.

Relationship Between Patient SWAP-200 Personality Characteristics and Therapist-Rated Therapeutic Alliance Early in Treatment.

In the present study, we assess the extent to which patient personality features and prototypes are associated with early treatment therapist-rated alliance. The study sample consisted of 94 patients receiving psychodynamic psychotherapy at an outpatient clinic. Clinicians completed the Working Alliance Inventory (J Couns Psychol 36:223-233; Psychother Res 9:405-423) to assess their views of early alliance and the Shedler-Westen Assessment Procedure 200 (SWAP-200; Assessment 5:333-353, Am J Psychiatry 161:1350-1365, 1743-1754; Am J Psychiatry 156:258-272, 273-285) to assess patient personality.

Clinical validity of prototype personality disorder ratings in adolescents.

A growing body of research shows that personality pathology in adolescents is clinically distinctive and frequently stable into adulthood. A reliable and useful method for rating personality pathology in adolescent patients has the potential to enhance conceptualization, dissemination, and treatment effectiveness. The aim of this study is to examine the clinical validity of a prototype matching approach (derived from the Shedler Westen Assessment Procedure-Adolescent Version) for quantifying personality pathology in an adolescent inpatient sample.

Relationship between SWAP-200 patient personality characteristics and patient-rated alliance early in treatment.

Research on the therapeutic alliance suggests patient personality characteristics to be plausible correlates of alliance formation. To date, research has largely focused on the relationship between the alliance and facets of patient personality measured via patient self-report, versus personality syndromes.In the present study, we assess patient personality using a clinician-rated measure-the Shedler-Westen Assessment Procedure-200 (SWAP-200; Shedler and Westen [Assessment 5:335-355, 1998; Am J Psychiatry 161:1350-1365, 2004; Am J Psychiatry 161:1743-1754, 2004]; Westen and Shedler [Am J Psychiatry 156:258-272, 1999; Am J Psychiatry 156:273-285, 1999])-and investigate the extent to which empirically derived personality configurations correlate with patient-rated alliance.

Convergent validity of the SWAP-200 dependency scales.

The present study examined the convergent validity of the Shedler-Westen Assessment Procedure Q-Sort (SWAP-200; ) dependency scales (Dependent Personality Disorder [DPD] Clinical Prototype and DPD composite description) by examining links between these variables with Inventory of Interpersonal Problems Circumplex Scales (IIP-C; Alden et al., 1990; Horowitz et al., 2000; Horowitz et al.

Kinetics and mechanism of the reaction of cysteine and hydrogen peroxide in aqueous solution.

The oxidation of thiol-containing small molecules, peptides, and proteins in the presence of peroxides is of increasing biological and pharmaceutical interest. Although such reactions have been widely studied there does not appear to be a consensus in the literature as to the reaction products formed under various conditions, the reaction stoichiometry, and the reaction mechanisms that may be involved. This study examines the reaction kinetics of cysteine (CSH) with hydrogen peroxide (H(2)O(2)) in aqueous buffers (in the absence of metal ions) over a wide range of pH (pH 4-13) and at varying ratios of initial reactant concentrations to explore the range of conditions in which a two-step nucleophilic model describes the kinetics.

Hydrolysis in pharmaceutical formulations.

This literature review presents hydrolysis of active pharmaceutical ingredients as well as the effects on dosage form stability due to hydrolysis of excipients. Mechanisms and measurement methods are discussed and recommendations for formulation stabilization are listed.