Scarf et al. (Proc Natl Acad Sci 113(40):11272-11276, 2016) demonstrated that pigeons, as with baboons (Grainger et al. in Science 336(6078):245-248, 2012; Ziegler in Psychol Sci.
View Article and Find Full Text PDFJ Pharmacol Exp Ther
October 2002
J Pharmacol Exp Ther
August 2002
Although CYP2C8, CYP2C9, and CYP2C19 play an important role in drug biotransformation, factors influencing the expression and activity of these CYP2C P450s in human liver remain largely undefined. We used primary cultures of human hepatocytes from 15 subjects to assess the inducibility of CYP2C enzyme expression by prototypical inducer agents, including rifampicin, dexamethasone, and phenobarbital. After culture for 72 h in serum-free medium on collagen, Western blotting revealed that CYP2C9 was the only CYP2C enzyme expressed at appreciable levels in untreated hepatocytes.
View Article and Find Full Text PDFWe report a failure to find a repetition deficit in recall following the rapid serial visual presentation (RSVP) of words within sentences, using adjectives rather than nouns as the critical items. In a series of experiments that ruled out participant and procedural differences as the source of the failure, both word class and list context were found to moderate the repetition deficit, but grammatical necessity did not. The presence in the list of sentences in which the repeated adjectives were separated by more than three words (i.
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