Publications by authors named "Scott R Wessels"

Background And Objectives: The purpose of this guideline is to update the 2010 American Academy of Neurology (AAN) brain death/death by neurologic criteria (BD/DNC) guideline for adults and the 2011 American Academy of Pediatrics, Child Neurology Society, and Society of Critical Care Medicine guideline for infants and children and to clarify the BD/DNC determination process by integrating guidance for adults and children into a single guideline. Updates in this guideline include guidance related to conducting the BD/DNC evaluation in the context of extracorporeal membrane oxygenation, targeted temperature management, and primary infratentorial injury.

Methods: A panel of experts from multiple medical societies developed BD/DNC recommendations.

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Article Synopsis
  • - Recent studies show that lecanemab can slow cognitive and functional decline in early Alzheimer's disease (AD), making it a promising treatment option alongside other monoclonal antibodies targeting β-amyloid.
  • - The introduction of these treatments involves significant risks and challenges that differ from current AD management, requiring changes in clinical practices and infrastructure for effective use.
  • - This article offers guidance for neurologists on implementing antiamyloid therapies, emphasizing patient selection, treatment monitoring, multidisciplinary collaboration, and the importance of evolving practices to improve patient outcomes.
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Objective: To identify the class of evidence for aducanumab use for the treatment of Alzheimer disease and present clinical considerations regarding use.

Methods: The author panel systematically reviewed available clinical trial data detailing aducanumab use in individuals with early symptomatic Alzheimer disease. Level of evidence statements were assigned in accordance with the American Academy of Neurology's 2017 therapeutic classification of evidence scheme.

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  • The objective of the study was to update the 2011 AAN guideline on treating painful diabetic neuropathy (PDN), focusing on both topical and oral medications.
  • The authors conducted a systematic review of literature from January 2008 to April 2020 to develop new practice recommendations.
  • The results highlighted that TCAs showed a large effect size for pain relief, while SNRIs and gabapentinoids also demonstrated significant effectiveness, but opioids are not recommended for treating PDN.
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Purpose: While there is strong evidence supporting the importance of telemedicine in stroke, its role in other areas of neurology is not as clear. The goal of this review is to provide an overview of evidence-based data on the role of teleneurology in the care of patients with neurologic disorders other than stroke.

Recent Findings: Studies across multiple specialties report noninferiority of evaluations by telemedicine compared with traditional, in-person evaluations in terms of patient and caregiver satisfaction.

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