Publications by authors named "Scott R Karlan"
Article Synopsis
- National guidelines suggest that older patients (≥65 years) with favorable invasive breast cancer can skip sentinel node biopsy (SNB) during treatment, but there's a lack of prospective studies on this.
- A study involved 125 ER+ breast cancer patients aged 65 and older who underwent breast-conserving surgery (BCS) without SNB, focusing on recurrence rates and survival outcomes.
- Results showed only 1.6% of patients experienced axillary recurrence, with high 3-year survival rates, supporting the idea that SNB may not be necessary for this demographic.
The use of MRI in preoperative staging of breast cancer has escalated recently. Breast MRI has greater sensitivity than mammography, ultrasound, and clinical examination in cancer detection. Because of its variable specificity, however, there has been concern that increased MRI use will result in increased rates of mastectomy for early-stage breast cancer.
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