Standardization of amniotic fluid leptin levels and utility in maternal overweight and fetal undergrowth.

Objective: Leptin is an adipokine that regulates energy homeostasis. The objective of this study was to establish a gestational age-specific standard for amniotic fluid leptin (AFL) levels and examine the relationship between AFL, maternal overweight and fetal growth restriction.

Study Design: Amniotic fluid was obtained at mid-gestation from singleton gravidas, and leptin was quantified using enzyme-linked immunosorbent assay.

Applying an organizational framework for health information technology to alerts.

We are far from understanding how best to design, implement, and use health information technology (IT). A comprehensive framework, developed by Rippen et al to capture and organize knowledge on the implementation, use, and optimization of health IT, may guide and inform more effective health IT deployment. This study applied Rippen's framework to a focused type of health IT - alerts - through clinical decision support (CDS), an area with a substantial evidence base around many facets of implementation, including the technology, use, and outcomes.

Promise of and potential for patient-facing technologies to enable meaningful use.

Patients are using healthcare technologies for a variety of reasons. Recently, the Meaningful-Use rule was released by the Centers for Medicare and Medicaid Services, providing some initial guidance for patient-facing technologies. There needs to be more of an understanding of patients' needs and how these technologies can be utilized effectively.

The aging of a clinical information system.

The senescence of a clinical information system is more likely to have administrative than technical bases. Supporting this claim is a case study of one aging oncology information system. The case study is qualitative, as behooves the subject matter.