In Vivo Confocal Microscopy Morphologic Features and Cyst Density in Acanthamoeba Keratitis.

Purpose: To correlate in vivo confocal microscopy morphologic features (IVCM-MF) and Acanthamoeba cyst density (ACD) with final best-corrected visual acuity (BCVA) in Acanthamoeba keratitis (AK).

Design: Retrospective cohort study.

Methods: Patient demographics, treatment outcome, and corresponding IVCM-MF performed at the acute stage of infection were analyzed.

Anterior Segment Optical Coherence Tomography Angiography and Optical Coherence Tomography in the Evaluation of Episcleritis and Scleritis.

: To evaluate the feasibility of using anterior segment optical coherence tomography (AS-OCT) and AS-OCT angiography (AS-OCTA) in assessing patients with episcleritis and scleritis.: Degree of vascularity [vessel density index (VDI)], measured with AS-OCTA, and sclera thickness [conjunctiva epithelium (CE), conjunctiva/episclera complex (CEC), and episclera/sclera complex (ESC)], measured with AS-OCT were compared.: A total of 37 eyes (13 episcleritis, 11 scleritis, 13 controls) were analyzed.

Changes in corneal aesthesiometry and the sub-basal nerve plexus in benign essential blepharospasm.

Background: The aetiology of blepharospasm remains unclear. There is evidence that the afferent pathway is important, but this area remains under-researched.

Aim: To explore the hypothesis that the afferent arm of the blink reflex is abnormal in blepharospasm by assessing a range of measures of corneal sensory function.

Evaluation of iris and iridociliary body lesions with anterior segment optical coherence tomography versus ultrasound B-scan.

Aims: To compare anterior segment optical coherence tomography (AS-OCT) with ultrasound B-scan (USB) in evaluating iris and iridociliary body lesions.

Methods: Image features and resolution comparison between AS-OCT and USB in 126 patients (126 eyes) presenting with iris or iridociliary body lesion. Bland-Altman plots were generated to assess the level of agreement between the two techniques.

In vivo confocal microscopy findings in central toxic keratopathy.

Central toxic keratopathy is an uncommon complication after laser in situ keratomileusis. We report the confocal microscopy findings in a case of central toxic keratopathy that confirm loss of keratocytes from the corneal stromal bed in the acute phase, with gradual repopulation over the following year.

In vivo confocal microscopy of bleb-like disorder in epithelial basement membrane dystrophy.

Purpose: To report the confocal microscopic appearance of bleb-like disorder in epithelial basement membrane dystrophy (EBMD).

Methods: Two subjects with bleb-like disorder in EBMD were examined with slit-lamp biomicroscopy and in vivo confocal microscopy using the Heidelberg Retina Tomograph II/Rostock Cornea Module. A sample obtained from epithelial debridement from 1 subject provided histologic correlation.

Quality of life in high myopia before and after implantable Collamer lens implantation.

Purpose: To examine changes in vision-related quality of life after implantable Collamer lens (ICL) implantation for the correction of myopia.

Design: Prospective, interventional, consecutive case series.

Participants: We included 34 consecutive patients (68% female; mean age, 37 years [range, 23-49]) with preoperative myopia (mean ± standard deviation [SD] refraction spherical equivalent, -11.

Diagnostic accuracy of microbial keratitis with in vivo scanning laser confocal microscopy.

Aims: To determine the accuracy of diagnosing microbial keratitis by masked medical and non-medical observers using the Heidelberg Retina Tomograph II/Rostock Cornea Module in vivo confocal microscope.

Methods: Confocal images were selected for 62 eyes with culture- or biopsy-proven infections. The cases comprised 26 Acanthamoeba, 12 fungus, three Microsporidia, two Nocardia and 19 bacterial infections (controls).

Presumed corneal argyrosis from occlusive soft contact lenses: a case report.

Purpose: To report a case of presumed corneal argyrosis associated with sliver nitrate-coated cosmetic soft contact lens wear.

Methods: A 67-year-old woman wore silver nitrate-coated occlusive soft lenses for 17 years for the management of intractable diplopia. Slit-lamp examination revealed a diffuse blue-gray deposit that was characteristic of corneal argyrosis just anterior to Descemet membrane.

Contact lens fitting following unsuccessful refractive surgery.

A retrospective review of case notes of consecutive patients referred to a contact lens clinic after unsuccessful refractive surgery was carried out to determine the success of contact lens fitting. The main outcome variables in determining success were visual improvement, contact lens tolerance, fitting characteristics and wearing time. Thirteen eyes were fitted with conventional rigid gas permeable (CRGP), 10 with soft and 19 with reverse geometry rigid gas permeable contact lenses (RVG).