Continuous Glucose Monitoring vs Fingerstick Monitoring for Hemoglobin A Control in Veterans.

Background: Patients with diabetes have traditionally been required to use fingerstick testing to self-monitor their glucose levels. However, continuous glucose monitors (CGMs) collect glucose readings throughout the day and display daily trends, which allow clinicians to individualize treatment to achieve hemoglobin A (HbA) goals and simplify medication regimens. While studies have shown that CGMs improve HbA levels compared to fingerstick testing, this research has focused on type 1 diabetes and excluded veterans and patients on insulin therapy.

Proton Pump Inhibitor Use and Risk of Dementia in the Veteran Population.

There was a statistically significant association between use of proton pump inhibitors and dementia diagnosis in a 11-year retrospective study of patients at the Sioux Falls Veteran Affairs Health Care System.

Impact of Tranexamic Acid on Blood Loss and Need for Blood Transfusions in Total Knee and Total Hip Arthroplasty.

Use of tranexamic acid during total knee and total hip arthroplasty procedures may safely and effectively reduce blood loss and the need for transfusions in patients.

Glutathione and mercapturic acid conjugates of sulofenur and their activity against a human colon cancer cell line.

Sulofenur is one of the diarylsulfonylureas developed as an anticancer agent. Sulofenur possesses a broad spectrum of activity in several solid tumor models and has undergone extensive clinical trials based on its impressive preclinical activity. However, the clinical response of sulofenur has been disappointing because of the side effect of anemia.