[Skeleton find from Roman times suspected as an homicide victim].

A human skeleton was found during construction work on the concrete foundations of a fence built 17 years before. The situation seemed to suggest that a corpse had been disposed of 17 years ago. Forensic and osteological examinations showed that death had been caused by semi-sharp and blunt craniocerebral trauma.

A natural rubber drainage tube with antithrombogenic lumen surface.

A drainage tube was made by radiation vulcanization of a high polymeric substance based on natural rubber elastomers. Pentosan polysulphate sodium bound to a carrier substance (synthetic type 4A or 13X zeolite) was incorporated in the drainage tube which was then tested for its anticoagulant properties during perfusion with Tris buffer solution, citrated plasma, and blood, resp. The amount of pentosan polysulphate sodium released from the tube walls during perfusion with human citrated plasma in an open circulatory system was sufficient to exert an anticoagulant effect on the streaming plasma.

[Exposure to asbestos dust and asbestosis of employees in a Thüringen rubber industry].

131 exposed people by dust of talc in rubber industry in Thuringia were examined by contrast to a same no examined group of working people. The asbestos in talc did cause in 26 (19.8%) cases of exposed people a pneumoconiosis.

Molecular cloning, sequencing and expression in Escherichia coli of the 25-kDa growth-related protein of Ehrlich ascites tumor and its homology to mammalian stress proteins.

The growth-related 25-kDa protein (p25) of Ehrlich ascites tumor (EAT) has been characterized by molecular cloning and sequencing of cDNA clones detected by hybridization with oligonucleotide probes synthesized according to the amino acid sequence of a tryptic peptide of p25. Detection of p25 mRNA in EAT of the exponential growth phase and of the stationary phase using cDNA-derived RNA probes demonstrated that the abundance of p25 mRNA is also growth-related. High-level expression of p25 in Escherichia coli has been established by oligonucleotide-directed mutagenesis of cDNA and insertion of the mutated cDNA into a T7-promoter expression vector.

Studies on elastomeric materials with incorporated antithrombotics.

Antithrombotically effective drugs (heparin, pentosan polysulphate, streptokinase) were incorporated into elastomeric materials by means of zeolites as carrier. The incorporated antithrombotic agents can be delivered to the surrounding medium. These self-antithrombotic elastomers may be used as tubes to drain off body fluids (catheters, drains, etc.

[Problems of exposure to organic mercury compounds in pregnancy].

On account of oral intake of mercury by contaminated foodstuff (eggs eaten by pregnant women) due to non-observance of legal decisions increased mercury concentrations in the maternal and infantile blood, in the urine and hair of the mother, in the placenta, the amnion, the cord blood and the breast milk could be proved in comparison to non-exposed pregnant women. Clinical and laboratory-chemical parameters did not show any symptoms of an intoxication in mothers and children. Demands for observance of the legal decisions and avoidance of professional dealing are particularly important for pregnant women.

[Health status and management of elderly citizens of a residential district and a home for the aged in the city of Erfurt].

Preservation, furtherance and recovery of health and great joy the old age - these are requests of social politics in GDR. The ageing may be influenced by a series of sanitary and social factors of risk. We have examined 100 townsmen in a home for aged people and 100 pensioners in housing-settlement of Erfurttown.

[Psychopathology of senile dementias in nursing home residents].

Examination of 163 nursing home residents revealed chronic brain syndrome of different amount in 84%. Demented patients with clinical evidence of arteriosclerosis had significantly higher values of emotional incontinence, dysphoria, depression and vegetative complaints than those without evidence of arteriosclerosis. Correlation of single psychopathologic parameters with other psychopathologic, neurologic and somatic variables resulted in very different correlation profiles for the following symptoms: emotional incontinence, apathy, dysphoria and euphoria.

[New aspects of chronic occupational manganese poisoning].

Wherever workers are professionally exposed to manganese and its compounds, but particularly in brown haematite mills, a chronic occupational manganese intoxication may appear with the picture of an expressed results of own investigations on 45 workers of a brown haematite mill in Thuringia who were exposed to manganic dust during 11 years as well as on manganese patients who were reported shall contribute to the clarification of the question of early diagnosis and differential diagnosis of a manganese intoxication. Attention is paid to functional diagnostic methods (EEG, EMG). On the basis of successes of treatment with the help of a substitution therapy of L-Dopa and amantine hydro-chloride new aspects concerning the pathogenesis of this disease are reported and conclusions for practice are made.