[Eosinophilia, diarrhea].

A 46-year-old Swiss woman presents with intermittent abdominal pain and persistent eosinophilia that is suggestive of helminthic etiology. Though her stay in Africa goes back > 35 years, an imported disease is a possibility. However, contact with a puppy suggests a locally acquired organism.

[Acute alveolitis due to mesalazine].

A 66-year-old male developed lymphocytic alveolitis with bronchiolitis after 3 month's treatment with mesalazin for ulcerative colitis. The patient's symptoms disappeared after halting mesalazin and increasing the steroid dose, the reduced diffusing capacity ameliorated and the thoracic X-ray normalized. The question whether this was a case of pulmonary involvement in inflammatory bowel disease or a drug side effect.

[Radiation proctocolitis following gynecologic radiotherapy: an endoscopic study].

The prevalence of radiation injuries was assessed in 155 of 206 surviving patients who had had radiation therapy for carcinoma of the uterus or vagina. The patients were examined according to a standardized protocol. 51 (32.

[Esophageal obstruction in tube feeding: a result of protein precipitation caused by antacids?].

A complication of tube feeding, i.e. thickening of nutrient solution in the presence of an antacid leading to obstruction of the esophagus, is reported.

[Antacids--gel or tablet. A randomized, double-blind, placebo-controlled study].

A double blind placebo controlled trial was conducted to compare the effect of two antacid brands (liquid and tablet form) on fasting and postprandial intragastric pH. In 9 healthy volunteers intragastric pH was continuously recorded by solid state memory on 6 occasions. 40 mmol of each antacid was given one hour before and after a standardized meal.

[Sclerotherapy of esophageal varices. Indications and results].

Injection sclerotherapy of esophageal varices is now firmly established. The indication and results are exemplified by the experience gained during the last 5 1/2 years at our institution. The early mortality rate within 30 days was 20% for patients needing emergency sclerotherapy during acute bleeding, and 4.

Adverse reactions following intravenous penicillin-G relate to degradation of the drug in vitro.

We have recently shown that high-dose intravenous therapy with penicillin-G always results in both sensitised lymphocytes and rise of anti-penicilloyl IgG antibodies. If penicillin-G is strictly given as freshly prepared bolus doses this sensitisation is prevented. In 193 patients, intravenous treatment with penicillin-G without special precautions (bolus doses stored up to 36 h at 4 degrees C or continuous infusions) led to 8.

[Amodiaquine-induced agranulocytosis in malaria prevention: demonstration of an amodiaquine-induced cytotoxic antibody against granulocytes].

A patient is presented who developed agranulocytosis while taking amodiaquine for suppressive therapy of malaria. An amodiaquine-dependent granulocytotoxic antibody could be demonstrated in the patient's serum on day 1 after stopping amodiaquine medication. Granulocyte transfusion was ineffective on days 6 and 7, possibly due to the slow elimination of the drug.

[Spontaneous radial segmentation of cell nuclei: morphologic marker of T-cell neoplasms?].

Radial segmentation (RS) of leukocyte nuclei has been observed, for example, in leukemias (Rieder cells). In 6 of 8 patients with T-ALL, RS of neoplastic cells was found in the peripheral blood, whereas in 14 patients with non-T-ALL no RS cells were present. RS may be a morphologic marker for certain T-cell neoplasms, and with regard to ultrastructure it seems to be identical to heat-induced RS of non-neoplastic cells.

[The problem of infectiousness of tuberculosis patients during chemotherapy].

In 1979 two patients with cavitary pulmonary tuberculosis were treated by a combination of three tuberculostatic drugs. During 12 1/2 and 16 1/2 weeks M. tuberculosis could be cultured in sputum and gastric juice respectively.