Going Viral: Assessing the Impact of Social Media on Enrollment in a Coronavirus Disease 2019 (COVID-19) Cohort Study.

Objective This study aimed to quantify the effect of social media posts on study enrollment among children with mild coronavirus disease 2019 (COVID-19). Methods The primary outcome was weekly study enrollments analyzed using a run chart. A secondary analysis used linear regression to assess study enrollments two days before and after a social media post, adjusted for the statewide pediatric seven-day-average severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case rate, social media posting day, and the interaction of these two variables.

Thermoresponsive Conductivity of Graphene-Based Fibers.

Smart materials are versatile material systems which exhibit a measurable response to external stimuli. Recently, smart material systems have been developed which incorporate graphene in order to share on its various advantageous properties, such as mechanical strength, electrical conductivity, and thermal conductivity as well as to achieve unique stimuli-dependent responses. Here, a graphene fiber-based smart material that exhibits reversible electrical conductivity switching at a relatively low temperature (60 °C), is reported.

Early Postoperative Opioid Requirement Is Associated With Later Pain Control Needs After Supratentorial Craniotomies.

Background: Despite a renewed focus in recent years on pain management in the inpatient hospital setting, postoperative pain after elective craniotomy remains under investigated. This study aims to identify which perioperative factors associate most strongly with postoperative pain and opioid medication requirements after inpatient craniotomy.

Materials And Methods: Using an existing dataset, we selected a restricted cohort of patients who underwent elective craniotomy surgery requiring an inpatient postoperative stay during a 7-year period at our institution (n=1832).

A 660-Kb deletion with antagonistic effects on fertility and milk production segregates at high frequency in Nordic Red cattle: additional evidence for the common occurrence of balancing selection in livestock.

In dairy cattle, the widespread use of artificial insemination has resulted in increased selection intensity, which has led to spectacular increase in productivity. However, cow fertility has concomitantly severely declined. It is generally assumed that this reduction is primarily due to the negative energy balance of high-producing cows at the peak of lactation.

Trans-sternal titanium fixation bars: an initial experience with 28 patients.

A clinical experience is described with the use of titanium trans-sternal fixation bars to achieve either primary or secondary sternal closure and stability using the principle of rigid fixation in high-risk and wound salvage sternotomy patients. The purpose of rigid fixation in those situations is not only to achieve rapid strong bone healing, but to improve respiratory function by restoring compliance and thoracic support for the lungs, especially in patients with severe pulmonary compromise. The system may be difficult and expensive to apply, but the positive results in most if not all the initial 28 patients appear to justify its use.

Mapping of fertility traits in Finnish Ayrshire by genome-wide association analysis.

A whole-genome scan using single marker association was used to detect chromosome regions associated with seven female fertility traits in Finnish Ayrshire dairy cattle. The phenotypic data consisted of de-regressed estimated breeding values for 340 bulls which were estimated using a single trait model. Genotypes were obtained with the Illumina BovineSNP50 panel and a total of 35 630 informative, high-quality single nucleotide polymorphism (SNP) markers were used.

Fine mapping of quantitative trait loci for mastitis resistance on bovine chromosome 11.

Quantitative trait loci (QTL) affecting clinical mastitis (CM) and somatic cell score (SCS) were mapped on bovine chromosome 11. The mapping population consisted of 14 grandsire families belonging to three Nordic red cattle breeds: Finnish Ayrshire (FA), Swedish Red and White (SRB) and Danish Red. The families had previously been shown to segregate for udder health QTL.

Quantitative trait loci for fertility traits in Finnish Ayrshire cattle.

A whole genome scan was carried out to detect quantitative trait loci (QTL) for fertility traits in Finnish Ayrshire cattle. The mapping population consisted of 12 bulls and 493 sons. Estimated breeding values for days open, fertility treatments, maternal calf mortality and paternal non-return rate were used as phenotypic data.

Joint analysis of quantitative trait loci for clinical mastitis and somatic cell score on five chromosomes in three Nordic dairy cattle breeds.

Five chromosomes were selected for joint quantitative trait loci (QTL) analyses for clinical mastitis (CM) and somatic cell score (SCS) in 3 breeds: Finnish Ayrshire (FA), Swedish Red and White (SRB), and Danish Red (DR). In total, 19 grandsires and 672 sons in FA, 19 grandsires and 499 sons in SRB, and 8 grandsires and 258 sons in DR were used in the study. These individuals were genotyped with the 61 microsatellite markers used in any of the previous QTL scans on the selected chromosomes.

The role of the bovine growth hormone receptor and prolactin receptor genes in milk, fat and protein production in Finnish Ayrshire dairy cattle.

We herein report new evidence that the QTL effect on chromosome 20 in Finnish Ayrshire can be explained by variation in two distinct genes, growth hormone receptor (GHR) and prolactin receptor (PRLR). In a previous study in Holstein-Friesian dairy cattle an F279Y polymorphism in the transmembrane domain of GHR was found to be associated with an effect on milk yield and composition. The result of our multimarker regression analysis suggests that in Finnish Ayrshire two QTL segregate on the chromosomal region including GHR and PRLR.

Linkage disequilibrium and selection response in two-stage marker-assisted selection of dairy cattle over several generations.

A stochastic simulation was carried out to investigate the advantage of marker-assisted selection (MAS) in comparison with traditional selection over several generations. The selection goal was a sex-limited trait or a linear combination of traits with a polygenic component, two unlinked additive QTL and a non-genetic component. The simulated QTL were moderate or large and the allele frequencies were varied.

Quantitative trait loci with parent-of-origin effects in chicken.

We investigated potential effects of parent-of-origin specific quantitative trait loci (QTL) in chicken. Two divergent egg-layer lines differing in egg quality were reciprocally crossed to produce 305 F2 hens. Searching the genome using models with uni-parental expression, we identified four genome-wide significant QTL with parent-of-origin effects and three highly suggestive QTL affecting age at first egg, egg weight, number of eggs, body weight, feed intake, and egg white quality.

Sternal wound reconstruction: 252 consecutive cases. The Lenox Hill experience.

The authors report on a personal experience of 252 consecutive secondary sternal wound closures resulting from a series of 11,601 median sternotomies at a single institution performed over a 14-year period. Protocols for treatment are described from the time of initial consultation with the plastic surgeon through the period of postoperative care. The patients and wounds were diverse and complex, with each factor requiring careful analysis before a treatment course was selected.

Quantitative trait Loci for health traits in Finnish Ayrshire cattle.

A whole-genome scan was conducted to search for quantitative trait loci (QTL) affecting health traits in Finnish Ayrshire dairy cattle. The mapping population consisted of 12 bulls and their 491 sons in a granddaughter design. A total of 150 markers were typed covering all 29 autosomes.

Quantitative trait loci affecting milk production traits in Finnish Ayrshire dairy cattle.

A whole genome scan of Finnish Ayrshire was conducted to map quantitative trait loci (QTL) affecting milk production. The analysis included 12 half-sib families containing a total of 494 bulls in a granddaughter design. The families were genotyped with 150 markers to construct a 2764 cM (Haldane) male linkage map.

A genome scan for quantitative trait loci affecting milk production in Norwegian dairy cattle.

An autosomal genome scan for quantitative trait loci (QTL) affecting milk production traits was carried out on the Norwegian Dairy Cattle population. Six half-sibling families with a total of 285 sons organized according to a granddaughter design were analyzed by a multiple marker regression method. Suggestive QTL for one or several of the five milk traits (milk yield, protein percentage, protein yield, fat percentage and fat yield) were detected on chromosomes 3, 5, 6, 11, 13, 18 and 20.

Assessment of tumor burden and treatment response by 18F-fluorodeoxyglucose injection and positron emission tomography in patients with cutaneous T- and B-cell lymphomas.

18F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) is a unique functional/metabolic imaging modality that is efficacious in nodal staging and detection of extranodal involvement for a variety of lymphomas. We report its novel use in evaluating tumor burden and response to therapy in two patients with cutaneous lymphomas. A 24-year-old woman with aggressive subcutaneous panniculitic T-cell lymphoma associated with fever, arthralgias, lymphadenopathy, mild anemia, and widespread painful lesions refractory to multiple treatment strategies exhibited intense uptake of a glucose analogue at sites of clinically apparent (and clinically imperceptible) disease.

Mapping of quantitative trait loci affecting quality and production traits in egg layers.

A mapping population segregating for egg quality traits was created by a line cross between two egg layer lines and screened by a genome scan. The F2 generation consisted of 307 hens, which were scored for egg quality and production traits. The mapping population was genotyped for 99 microsatellite loci, spanning nine macrochromosomes and five small linkage groups.

Quantitative trait loci affecting clinical mastitis and somatic cell count in dairy cattle.

Norway has a field recording system for dairy cattle that includes recording of all veterinary treatments on an individual animal basis from 1978 onwards. Application of these data in a genome search for quantitative trait loci (QTL) verified genome-wise significant QTL affecting clinical mastitis on Chromosome (Chr) 6. Additional putative QTL for clinical mastitis were localized to Chrs.

The right angle rhytidectomy flap.

A detailed description of a simple technique to minimize scarring and hairline elevation following rhytidectomy is provided. The technique is illustrated with a step-by-step account of planning and performance.

The Aufricht geometric breast reduction revisited.

The concepts and techniques describing a geometric breast reduction were first reported by Dr Gustrave Aufricht almost 50 years ago. In his presentations of 1948 and 1949 he described in detail his concept of breast reduction markings. Less obvious in these papers was his description of a central- and inferior-based pedicle preserving nipple viability.

Identification of quantitative trait loci for prolificacy and growth in mice.

Marker-quantitative trait locus (QTL) linkage was evaluated in F2 intercross and backcross mouse populations derived from stocks differing dramatically in prolificacy and mature weight. A highly prolific outbred Quackenbush-Swiss mouse line, or an inbred line derived from it (16.62 +/- 0.

Aesthetic surgical training: the Lenox Hill model.

This program enhances residency training in aesthetic surgery. It provides hands-on operating experience in a supervised hospital setting. Concerns of financial support and liability are addressed.

Medical complications following successful pediatric dental treatment.

Dental treatment is usually performed without any development of medical sequela. However, patients can acquire serious, life threatening complications, even though successful dental treatment is completed. This paper presents four case reports of medical complications following routine pediatric dental treatment.